The RSNA reporting language has significant diagnostic performance for identifying COVID-19 pneumonia. CT findings that do not exactly fit the RSNA reporting language, such as "single, round GGO" and "single, peripheral GGO" improve diagnostic performance.The RSNA reporting language has significant diagnostic performance for identifying COVID-19 pneumonia. CT findings that do not exactly fit the RSNA reporting language, such as "single, round GGO" and "single, peripheral GGO" improve diagnostic performance.Traumatic brain injury (TBI) causes brain damage, which involves primary and secondary injury mechanisms. Primary injury causes local brain damage, while secondary damage begins with inflammatory activity followed by disruption of the blood-brain barrier (BBB), peripheral blood cells infiltration, brain edema, and the discharge of numerous immune mediators including chemotactic factors and interleukins. TBI alters molecular signaling, cell structures, and functions. Besides tissue damage such as axonal damage, contusions, and hemorrhage, TBI in general interrupts brain physiology including cognition, decision-making, memory, attention, and speech capability. Regardless of the deep understanding of the pathophysiology of TBI, the underlying mechanisms still need to be assessed with a desired therapeutic agent to control the consequences of TBI. The current review gives a brief outline of the pathophysiological mechanism of TBI and various biochemical pathways involved in brain injury, pharmacological treatment approaches, and novel targets for therapy.This review systematically explored structural, functional, and metabolic features of the cisgender brain compared with the transgender brain before hormonal treatment and the heterosexual brain compared to the homosexual brain from the analysis of the neuroimaging literature up to 2018, and identified and discussed subsequent studies published up to March 2021. read more Our main aim was to help identifying neuroradiological brain features that have been related to human sexuality to contribute to the understanding of the biological elements involved in gender identity and sexual orientation. We analyzed 39 studies on gender identity and 24 on sexual orientation. Our results suggest that some neuroanatomical, neurophysiological, and neurometabolic features in transgender individuals resemble those of their experienced gender despite the majority resembling those from their natal sex. In homosexual individuals the majority resemble those of their same-sex heterosexual population rather than their opposite-sex heterosexual population. However, it is always difficult to interpret findings with noninvasive neuroimaging. Given the gross nature of these measures, it is possible that more differences too subtle to measure with available tools yet contributing to gender identity and sexual orientation could be found. Conflicting results contributed to the difficulty of identifying specific brain features which consistently differ between cisgender and transgender or between heterosexual and homosexual groups. The small number of studies, the small-to-moderate sample size of each study, and the heterogeneity of the investigations made it impossible to meta-analyze all the data extracted. Further studies are necessary to increase the understanding of the neurological substrates of human sexuality.Although polyamorous relationships have received increasing attention from researchers over the past decade, little attention has been paid to differences in relationship configurations some individuals arrange their relationships hierarchically, prioritizing a primary partner; other relationship structures are non-hierarchical with no relationships prioritized over others. Across two samples (NStudy1= 225; NStudy2= 360), we compared relationship satisfaction and attachment security between individuals in hierarchical and non-hierarchical configurations. Greater variability in attachment security was found between partners in hierarchical relationships than those in non-hierarchical relationships; no significant differences were found in variability in relationships satisfaction across these groups. Furthermore, individuals in hierarchical relationships reported lower overall relationship satisfaction and attachment security compared to individuals in non-hierarchical relationships. More specifically, although no significant differences were found between non-hierarchical and primary partners, participants reported lower relationship satisfaction and attachment security with secondary and tertiary partners compared to non-hierarchical and primary partners. Findings suggest that these differences may attenuate with time. Although previous research has found that differences (e.g., in investment) between partners exist in both non-hierarchical and hierarchical configurations, the current research suggests that differences that occur organically rather than in a predetermined manner may be related to greater similarities in attachment security across partners as well as greater overall levels of relationship satisfaction and attachment security for individuals in non-hierarchical configurations. More research is needed to determine whether the observed between-partner differences are consistent with the relationship goals of individuals in hierarchical relationships.Disagreement over whether life is inevitable when the conditions can support life remains unresolved, but calculations show that self-organization can arise naturally from purely random effects. Closure to efficient causation, or the need for all specific catalysts used by an organism to be produced internally, implies that a true model of an organism cannot exist, though this does not exclude the possibility that some characteristics can be simulated. Such simulations indicate that there is a limit to how small a self-organizing system can be much smaller than a bacterial cell, but around the size of a typical virus particle. All current theories of life incorporate, at least implicitly, the idea of catalysis, but they largely ignore the need for metabolic regulation.