040, sensitivity 53%, negative predictive value 81%) and Leeds/Wittekind circumferential margin status (p = 0.050, sensitivity 73%, negative predictive value 79%) as compared to established borderline resectability definition criteria. Perivascular SMA stranding qualified as an independent negative prognostic parameter (HR 3.066, 95% CI 1.078-5.716, p = 0.036). Conclusion The radiological evaluation of any SMPV alteration and perivascular SMA stranding predicts R status and overall survival in PDAC patients, and may serve to identify potential candidates for neoadjuvant therapy.We appreciate your comments and concerns about our manuscript in IJERPH on Bladder Health Experiences, Perceptions and Knowledge of Sexual and Gender Minorities [...].With the advent of unmanned aerial vehicles (UAVs), a major area of interest in the research field of UAVs has been vision-aided inertial navigation systems (V-INS). In the front-end of V-INS, image processing extracts information about the surrounding environment and determines features or points of interest. With the extracted vision data and inertial measurement unit (IMU) dead reckoning, the most widely used algorithm for estimating vehicle and feature states in the back-end of V-INS is an extended Kalman filter (EKF). An important assumption of the EKF is Gaussian white noise. In fact, measurement outliers that arise in various realistic conditions are often non-Gaussian. A lack of compensation for unknown noise parameters often leads to a serious impact on the reliability and robustness of these navigation systems. To compensate for uncertainties of the outliers, we require modified versions of the estimator or the incorporation of other techniques into the filter. The main purpose of this paper is to develop accurate and robust V-INS for UAVs, in particular, those for situations pertaining to such unknown outliers. Feature correspondence in image processing front-end rejects vision outliers, and then a statistic test in filtering back-end detects the remaining outliers of the vision data. For frequent outliers occurrence, variational approximation for Bayesian inference derives a way to compute the optimal noise precision matrices of the measurement outliers. The overall process of outlier removal and adaptation is referred to here as "outlier-adaptive filtering". Even though almost all approaches of V-INS remove outliers by some method, few researchers have treated outlier adaptation in V-INS in much detail. Here, results from flight datasets validate the improved accuracy of V-INS employing the proposed outlier-adaptive filtering framework.Dissolved oxygen (DO) content is an essential indicator for evaluating the quality of the water body and the main parameter for water quality monitoring. The development of high-precision DO detection methods is of great significance. This paper reports an integrated optofluidic device for the high precision measurement of dissolved oxygen based on the characteristics of silver nanoprisms. Metal nanoparticles, especially silver nanoprisms, are extremely sensitive to their surroundings. In glucose and glucose oxidase systems, dissolved oxygen will be transformed into H2O2, which affects the oxidation and erosion process of nanoprisms, then influences the optical properties of nanoparticles. By detecting the shift in the plasma resonance peak of the silver nanoparticles, the dissolved oxygen (DO) content can be determined accurately. Great reconfigurability is one of the most significant advantages of the optofluidic device. By simply adjusting the flow rate ratio between the silver nanoprisms flow and the water sample flow, real-time continuous adjustment of the detection ranges of DO from 0 to 16 mg/L can be realized dynamically. The detection limit of this device is as low as 0.11 µM (3.52 µg/L) for DO measurement. Thus, the present optofluidic system has a wide range of potential applications in fields of biomedical analyses and water sensing.Hawthorn belongs to the Crataegus genus of the Rosaceae family and is an important medicinal plant. Due to its beneficial effects on the cardiovascular system and its antioxidant and antimicrobial activity hawthorn has recently become quite a popular herbal medicine in phytotherapy and food applications. this website In this study, physicochemical characterization (color parameters, pH, titratable acidity, total soluble solids, soluble carbohydrate, total carotenoid, total phenols, and flavonoid contents), antioxidant activity (by ferric-reducing antioxidant power, FRAP assay), and quantification of some individual phenolic compounds of fruits of 15 samples of different hawthorn species (Crataegus spp.) collected from different regions of Iran were investigated. According to findings, the total phenols, total flavonoid content, and antioxidant activity were in the range of 21.19-69.12 mg gallic acid equivalent (GAE)/g dry weight (dw), 2.44-6.08 mg quercetin equivalent (QUE)/g dw and 0.32-1.84 mmol Fe++/g dw, respectively. Hyperoside (0.87-2.94 mg/g dw), chlorogenic acid (0.06-1.16 mg/g dw), and isoquercetin (0.24-1.59 mg/g dw) were found to be the most abundant phenolic compounds in the extracts of hawthorn fruits. The considerable variations in the antioxidant activity and phenolic compounds of hawthorn species were demonstrated by our results. Hence, the evaluation of hawthorn genetic resources could supply precious data for screening genotypes with high bioactive contents for producing natural antioxidants and other phytochemical compounds valuable for food and pharma industries.Osmanthus fragrans 'Yinbi Shuanghui' not only has a beautiful shape and fresh floral fragrance, but also rich leaf colors that change, making the tree useful for landscaping. In order to study the mechanisms of color formation in O. fragrans 'Yinbi Shuanghui' leaves, we analyzed the colored and green leaves at different developmental stages in terms of leaf pigment content, cell structure, and transcriptome data. We found that the chlorophyll content in the colored leaves was lower than that of green leaves throughout development. By analyzing the structure of chloroplasts, the colored leaves demonstrated more stromal lamellae and low numbers of granum thylakoid. However, there was a large number of plastoglobuli. Using transcriptome sequencing, we demonstrated that the expression of differentially expressed genes (DEGs) involved in chlorophyll degradation was upregulated, i.e., heme oxygennase-1 (HO1), pheophorbide a oxidase (PAO), and chlorophyllase-2 (CLH2), affecting the synthesis of chlorophyll in colored leaves.