The occurrence of depressive disorders in patients with cancers at the hospital was high. Their assessment and treatment should be prioritized to ensure complete management of the patients with cancer conditions.The occurrence of depressive disorders in patients with cancers at the hospital was high. Their assessment and treatment should be prioritized to ensure complete management of the patients with cancer conditions.This study aimed to elucidate changes in spatiotemporal and ground reaction force (GRF) variables during 90-m overground decelerated sprinting and determinants of the decrease in running speed. selleck inhibitor In 14 sub-elite male sprinters, a virtual 90-m sprint was reconstructed during which spatiotemporal and GRF variables were averaged for four steps in maximal speed (45.8-m mark) and deceleration (76.5-m mark) phases. With decreases in running speed (3.5 ± 1.1%) from the maximal speed to deceleration phases, step frequency (SF) (3.5 ± 1.9%), net anteroposterior mean force (64.4 ± 15.9%), and propulsive and vertical mean forces during the propulsive phase (3.5 ± 3.8% and 5.3 ± 3.3%) decreased, and support (ST) (2.9 ± 2.5%) and flight times (FT) (4.3 ± 3.3%), braking mean force (7.3 ± 4.0%), and effective vertical impulse during the entire support (5.1 ± 3.4%) and braking phases (20.6 ± 11.2%) increased. In addition, the decrease in running speed was associated with changes in SF, ST, and net anteroposterior mean force (r = .667, -.713, and .524, respectively). The current results demonstrate that decreases in running speed during short-distance overground sprinting are probably caused by decreases in SF through increases in ST and FT, as well as impairment of the ability to minimize braking force and maintaining propulsive force. A compromised ability to maintain the magnitude of applied force during the propulsive phase and the necessity for lengthening FT may cause greater braking force, which increases effective vertical impulse during the braking and entire support phases. The SF, ST, and net anteroposterior mean force are determinants of the magnitudes of decreases in running speed during short-distance overground sprinting.Eukaryotic genes can be classified into intronless (no introns), intron-poor (three or fewer introns per gene) or intron-rich. Early eukaryotic genes were mostly intron-rich, and their alternative splicing into multiple transcripts, giving rise to different proteins, might have played pivotal roles in adaptation and evolution. Interestingly, extant plant genomes contain many gene families with one or sometimes few sub-families with genes that are intron-poor or intronless, and it remains unknown when and how these intron-poor or intronless genes have originated and evolved, and what their possible functions are. In this study, we identified 33 such gene families that contained intronless and intron-poor sub-families. Intronless genes seemed to have first emerged in early land plant evolution, while intron-poor sub-families seemed first to have appeared in green algae. In contrast to intron-rich genes, intronless genes in intron-poor sub-families occurred later, and were subject to stronger functional constraints. Based on RNA-seq analyses in Arabidopsis and rice, intronless or intron-poor genes in AP2, EF-hand_7, bZIP, FAD_binding_4, STE_STE11, CAMK_CAMKL-CHK1 and C2 gene families were more likely to play a role in response to drought and salt stress, compared with intron-rich genes in the same gene families, whereas intronless genes in the B_lectin and S_locus_glycop gene family were more likely to participate in epigenetic processes and plant development. Understanding the origin and evolutionary trajectory, as well as the potential functions, of intronless and intron-poor sub-families provides further insight into plant genome evolution and the functional divergence of genes.Trauma-exposed individuals are at risk of developing mental health problems, including posttraumatic stress disorder (PTSD). As an exposed individual's friend or family member may be the first person to provide posttrauma relief, informing and training laypeople in psychosocial first aid may benefit mental health outcomes of trauma-exposed individuals. We aimed to (a) collect the best available evidence on communication as a first aid intervention in assisting individuals following traumatic events and (b) formulate practical recommendations. Systematic literature searches were conducted in three databases (March 2019). Following study selection, the extracted data were tabulated and synthesized narratively. The evidence was appraised according to the GRADE methodology and evaluated by a multidisciplinary expert panel to formulate recommendations for practice. Out of 1,724 articles, no experimental studies were identified, showing a complete lack of high-quality controlled studies on the efficacy of communicative practices. However, when lower-quality study designs were included, nine cross-sectional studies constituted the best available evidence. The studies suggested that positive communication by family members, r = -.38, aOR = 0.26, β = -.22, p less then .001-p less then .05, and expressive coping by the victim, β = -.62, p less then .001, were associated with PTSD diagnosis and/or symptom severity; however, the evidence was of very low certainty. The expert panel took the methodological limitations into account when formulating weak practical recommendations. Cross-sectional studies currently provide the best possible evidence for developing guidelines on psychosocial first aid. High-quality controlled studies are needed to establish casual associations and identify the most effective interventions.Dermatophyte infections usually present as various types of superficial cutaneous mycoses; on very rare occasions, dermatophytes enter deep into the dermis and cause invasive infections. In this study, we aimed to perform a systematic review of all reported invasive dermatophytosis cases over the past 20 years. We performed systematic searches in PubMed/Medline, EMBASE and Web of Science and identified 123 papers reporting 160 individual cases of invasive dermatophytosis between 2000 and 2020. Our study included 103 (64.4%) males, and the mean age at diagnosis was 43.0 years (range 3-87 years). The most common predisposing factor was superficial dermatophytosis (56.9%), followed by solid organ transplantation (26.9%), the use of topical immunosuppressants (15.6%), gene mutations (14.4%), diabetes (14.4%) and trauma (6.9%). Trichophyton (T.) rubrum was the most prevalent pathogen (53.1%) responsible for invasive dermatophytosis, followed by T. mentagrophytes (7.5%), Microsporum canis (6.9%), T. tonsurans (5.6%), T.