After 16 months of follow-up, progression-free survival of the control group was lower than that of the H2-only group, and significantly lower than that of H2 + chemotherapy, H2 + targeted therapy, and H2 + immunotherapy groups. In the combined-therapy groups, most drug-associated adverse events decreased gradually or even disappeared. H2 inhalation was first discovered in the clinic that can be used to control tumor progression and alleviate the adverse events of medications for patients with advanced non-small cell lung cancer. This study was approved by the Ethics Committee of Fuda Cancer Hospital of Jinan University on December 7, 2018 (approval No. Fuda20181207), and was registered at ClinicalTrials.gov (Identifier NCT03818347) on January 28, 2019.Widely distributed electrolytic-generators for hydrogen-water are not fully considered for the dependencies of post-electrolytic values of the dissolved hydrogen concentration (DH) and the oxidation-reduction potential (ORP) on the properties of the pre-electrolytic water. We investigated the dependencies of DH and ORP on mineral-based hardness, temperatures and the container materials, and effects on the oral cavity by oral washing or drinking. Along with an increase in mineral-based water-hardness, DH decreased from 960 to 870 μg/L and the ORP unexpectedly increased from -460 to -320 mV. Purified water of almost zero hardness, however, caused a post-electrolytic DH as low as 80 μg/L and an ORP as high as +20 mV. Post-electrolytic DHs were not significantly changed (780-900 μg/L) upon electrolysis at 1.5-30°C and decreased at 40-50°C. The diffusion of hydrogen from the inside to the outside of the container was extremely small even after 12 hours for an aluminum- or stainless steel-made container, but not fonese Center for Anti-Aging Medical Sciences (approval No. 09S02) on May 2, 2012.It is well known that low fresh gas flows result in lower cost of inhalational agents. A new generation of carbon dioxide absorbents allows low flow anesthesia with all anesthetics but these new compounds are more expensive. This study examines the cost of inhalational anesthesia at different fresh gas flows combined with the cost of absorbent. The cost of sevoflurane and desflurane is lower at low fresh gas flows. Paradoxically the cost of isoflurane is cheaper at 2 L/min than at lower fresh gas flows due to increased cost of carbon dioxide absorbent. Therefore low fresh gas flows should be used when feasible with sevoflurane and desflurane, but higher fresh gas flows up to 2 L/min may be more economical with isoflurane during maintenance phase of anesthesia.This study was performed to summarize our clinical experience with testicular descent and fixation through a scrotal stria incision for the treatment of palpable cryptorchidism in children. This study included 1034 children with palpable cryptorchidism from March 2009 to March 2019. A scrotal stria incision was used to perform testicular descent and fixation. Overall, 1020 children successfully underwent surgical testicular descent and fixation through a scrotal stria incision, and 14 patients underwent conversion to inguinal incision surgery. All patients were discharged 1-2 days after the operation. During hospitalization and follow-up, 55 patients developed complications, including 10 patients with testicular retraction, 7 with poor healing of the incision, and 38 with a scrotal hematoma. No patients developed testicular atrophy, an indirect inguinal hernia, or a hydrocoele. Testicular descent and fixation through a scrotal stria incision for the treatment of palpable cryptorchidism in children is safe and feasible in well-selected cases. This method has the advantages of no scarring and a good cosmetic effect.The real time estimation of effluent indices of papermaking wastewater is vital to environmental conservation. Ensemble methods have significant advantages over conventional single models in terms of prediction accuracy. As an ensemble method, multi-grained cascade forest (gcForest) is implemented for the prediction of wastewater indices. Compared with the conventional modeling methods including partial least squares, support vector regression, and artificial neural networks, the gcForest model shows prediction superiority for effluent suspended solid (SSeff) and effluent chemical oxygen demand (CODeff). In terms of SSeff, gcForest achieves the highest correlation coefficient with a value of 0.86 and the lowest root-mean-square error (RMSE) value of 0.41. In comparison with the conventional models, the RMSE value using gcForest is reduced by approximately 46.05% to 50.60%. In terms of CODeff, gcForest achieves the highest correlation coefficient with a value of 0.83 and the lowest root-mean-square error value of 4.05. In comparison with the conventional models, the RMSE value using gcForest is reduced by approximately 10.60% to 18.51%.Bismuth oxyhalides (BiOXs, X = Cl, Br and I) are emerging photocatalytic materials with unique layered structure, flexible band structure and superior photocatalytic activity. The purpose of this study was to develop a facile alcoholysis route to prepare BiOClxI1-x nanosheet solid solutions at room temperature. BX-795 nmr X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), UV-vis diffuse reflectance spectroscopy (UV-vis DRS), photoluminescence emission spectroscopy (PL) and Brunauer-Emmett-Teller (BET) surface area analyzer were used to characterize the as-prepared photocatalysts. These results revealed that two-dimension BiOClxI1-x nanosheet solid solutions could be obtained with high percentage of 001 crystal facets exposed. Moreover, the formation of solid solution could regularly change the optical absorption thresholds and band gaps of BiOClxI1-x photocatalysts. The photocatalytic experiments indicated that BiOCl0.75I0.25 exhibited the highest photocatalytic performance for the degradation of Rhodamine B (RhB) under simulated sunlight irradiation and the photocatalytic process followed a pseudo-first-order kinetic equation. A possible mechanism of RhB photodegradation over BiOClxI1-x solid solutions was proposed based on the structural properties of BiOClxI1-x solid solutions and RhB photosensitization.