5%) were diagnosed with TBLC (p ? 0.001). Hemorrhage was observed in 39 patients (47.6%), but only one had a massive hemorrhage. Pneumothorax was observed in 6 patients (7.3%) and none of them re-quired tube drainage. Conclusion Transbronchial lung cryobiopsy is a promising technique for the diagnosis of parenchymal lung diseases compared to transbronchial lung biopsy.Background/aim Paroxysmal nocturnal hemoglobinuria (PNH) is a very rare clonal hematopoietic stem cell disease characterized by chronic hemolytic anemia and thrombosis. We report data from a study of the occurrence of PNH among patients with idiopathic portal vein thrombosis (PVT). Materials and methods Patients who were followed up with the diagnosis of idiopathic PVT were enrolled into this study. Those with laboratory and/or imaging evidence of any local or systemic factor that could lead to PVT were excluded. PNH clone was examined in all patients using established FLAER methodology. Results A total of 112 patients (42 males and 70 females), none of them had a markedly PNH clone, but 4 patients (3.6%) with confirmed tests two times had small PNH clones (size between 3.02% and 4.62%). The median ages of PNH clone (-) and PNH clone (+) patients were 42 (range; 24-59) vs 39 (range; 36-42) years, respectively. The median hemoglobin concentration, platelet count and leukocyte count were lower in the PNH clone (+) group than the PNH clone (-) group. Anemia, thrombocytopenia, and leukopenia were detected in all PNH clone (+) patients. In addition, the PNH clone positivity size in monocytes was higher than erythrocytes in all of 4 patients. Conclusions PNH should be considered during differential diagnosis among patients with idiopathic PVT. Small PNH clones can be detected in PVT patients that we cannot clearly determine its relationship with PVT. We need furthermore studies to explore the potential role of this finding.Aim To investigate possible protective effects of Ankaferd Blood Stopper® (ABS) in an experimental liver IRI model. Methods The study was carried out on 30 female rats separated into 3 groups as sham, control (IRI), and treatment (IRI+ABS) groups. In IRI+ABS group, 0.5 ml/day ABS was given for 7 days before surgery. In IRI and IRI+ABS groups, hepatic pedicle was clamped for 30 minutes to apply ischemia. Then, after opening the clamp, 90-minute reperfusion of the liver was provided. The samples of blood and liver tissue were collected to conduct biochemical and histopathological analyses. Results Compared to sham group, IRI group had significantly higher levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total oxidant status (TOS), malondialdehyde (MDA), fluorescent oxidant products (FOP) and lower expression of albumin and total antioxidant status (TAS) (p less then 0,05). Compared to IRI group, IRI+ABS group showed lower expression of AST, ALT, TOS, MDA and FOP and higher expression of albumin and TAS (p less then 0.05). In histopathological analysis, congestion scores were statistically significantly lower in IRI+ABS group than IRI group. Conclusions ABS has a strong hepatoprotective effect thanks to its antioxidant and anti-inflammatory effects and could therefore be used as a potential therapeutic agent for IRI.Purpose The main purpose of this study is to evaluate the resting state hippocampal connectivity with language areas and to correlate them with laterality index calculations on single subject basis, hence to present hippocampal lateralization for language with rs-fMRI. Methods Task based and rs-fMRI data were gathered from a total of 45 subjects in 3T scanner. Brainvoyager QX, SPM and CONN softwares were used for data analysis. LI score of each subject was calculated and converted into normalized LI score (nLI). Intrahemispheric rs-connectivity analysis was performed between hippocampus and Broca regions on both sides. find more Correlation between these variables was measured with SPSS software. Results Right-TLE patients were found to have highest whereas left-TLE group were found to have lowest mean LI scores. Regarding hippocampo-lingual networks; left intrahemispheric connectivity values showed strong positive correlation with nLI values in left, right-TLE patients and healthy controls (p=0.035, 0.014, 0.047). There were no significant correlation between right intrahemispheric connectivity values and nLI scores in all groups. Conclusion This study seems to depict the existence of resting state hippocampo-lingual functional network which correlates well with lateralization of language function in the left hemisphere in both temporal lobe epilepsy patients and healthy controls.Background/aim The predictability of clinical outcomes in hypertension in specific patient groups, especially underrepresented populations is the key to rational treatment. This study aimed to investigate the impact of baseline characteristics of less then 65-year-old hypertensive women with an increased risk of cardiovascular events, managed with standard- or intensive-approach, on their clinical outcomes and serious adverse events (SAEs). Materials and methods Baseline characteristics of less then 65-year-old hypertensive women (n=1247) in SPRINT, a multicenter randomized trial to compare standard and intensive antihypertensive treatment, were analyzed with Cox-regression method to determine potential predictors of the clinical outcomes and SAEs. The primary outcome was the composite of myocardial infarction (MI), non-MI acute coronary syndrome, stroke, heart failure, or cardiovascular death. Results The primary outcome occurred in 3.1% and SAEs in 27.6% of the population. The treatment groups were similahypertensive management that promotes better outcomes in this middle-aged female population.Background Novel coronavirus 19 infection (COVID-19) has become a global pandemic and Turkey had the first coronavirus patient tested positive in 10 March 2020. Aims In this analysis we have discussed the characteristics of Turkish patients who have been hospitalized for COVID-19 infection. Study design Cross sectional study Methods This retrospective study included all the patients who have been hospitalized for novel coronavirus at blinded for peer review -Department of Internal Medicine between 15th March 2020 and 28th March 2020. Patients were screened with real time PCR (2019nCoV), chest X-ray and computer tomography. Also, their demographic characteristics including sex, age, occupation, comorbid disease etc. were recorded. Results There were 70 patients for analysis. Thirty-seven patients (52.9 %) tested positive for coronavirus infection with PCR. Mean age was 55.8 (min 24- max 87). There were 49 men (70.0%). Two patients (2%) were sent home and eleven patients (15.7%) were transferred to intensive care unit (ICU).