A Division I collegiate softball catcher presented with discoloration, coolness, and swelling of her left index finger that worsened with sport participation. Upper extremity arteriogram revealed absent flow to the radial aspect of the finger and compromise of the ulnar digital artery distal to the proximal interphalangeal joint. After failing nonoperative management, she underwent periarterial sympathectomy with relief of symptoms. Repetitive trauma to a catcher's hand can result in vascular compromise. When nonoperative measures fail, surgical intervention may be successful. We describe successful treatment using sympathectomy. Surgeons should be able to diagnose this condition and understand treatment options.Repetitive trauma to a catcher's hand can result in vascular compromise. When nonoperative measures fail, surgical intervention may be successful. We describe successful treatment using sympathectomy. Surgeons should be able to diagnose this condition and understand treatment options. A 47-year-old healthy man underwent cervical disc arthroplasty (CDA) for a C6 radiculopathy. Two-week radiographs showed a well-positioned implant. At the 6-week postoperative visit, the inferior portion of the implant had displaced ventrally, with C6 anterior vertebral body collapse. The next day, the implant was removed and converted to a C5/6 anterior cervical discectomy and fusion. Bone biopsy was unremarkable. This is the first reported case of early catastrophic failure of a well-positioned CDA in a healthy patient with good bone quality. Possible contributing mechanisms include hypermobility and anterior bone loss, factors previously associated with CDA.This is the first reported case of early catastrophic failure of a well-positioned CDA in a healthy patient with good bone quality. Possible contributing mechanisms include hypermobility and anterior bone loss, factors previously associated with CDA. A 9-year-old girl presented with a painful stiff elbow consequent to an injury she had sustained 4 months ago. The radiographs were suggestive of a type 2 Monteggia equivalent injury. She underwent an open reduction of the radial neck fracture and proximal ulna extension osteotomy to restore radiocapitellar alignment. At one-year follow-up, the child had a painless elbow with a good functional outcome. Monteggia lesions can be frequently missed and result in significant morbidity. Obtaining appropriate radiographs for a comprehensive understanding of the injury and proper surgical planning is important for achieving a good functional outcome in such injuries.Monteggia lesions can be frequently missed and result in significant morbidity. Obtaining appropriate radiographs for a comprehensive understanding of the injury and proper surgical planning is important for achieving a good functional outcome in such injuries. The present study aimed to evaluate the accuracy of the Omron HEM-7600T automated oscillometric upper-arm blood pressure (BP) monitor according to the American National Standards Institute/Association for the Advancement of Medical Instrumentation/International Organization for Standardization (ANSI/AAMI/ISO) 81060-22013 protocol. We recruited individuals until we obtained 86 eligible participants whose BP levels and ranges of arm circumference met the BP distribution requirements specified by the ANSI/AAMI/ISO. In each individual, we sequentially measured systolic and diastolic blood pressures (DBPs) using a mercury sphygmomanometer (two observers) and the HEM-7600T device (one supervisor) in the left upper arm. Data analysis was performed according to the ANSI/AAMI/ISO guidelines. A total of 101 individuals were recruited, and 86 were finally included in the analysis. For validation criterion 1, the mean ± SD of the differences between the test device and reference BP was -0.6 ± 6.6/1.0 ± 6.5 mmHg (systolic/diastolic). The data were in accordance with criterion 1 of the ANSI/AAMI/ISO 81060-22013 standard requirements (≤ 5 ± ≤ 8 mmHg). In addition, the mean device-observer difference in the 86 participants was -0.6 ± 5.65 mmHg for systolic blood pressure and 1.0 ± 5.96 mmHg for DBP, fulfilling criterion 2 with an SD of ≤6.91 mmHg for systolic blood pressure and ≤6.87 mmHg for DBP. The Omron HEM-7600T BP monitor fulfilled the requirements of the ANSI/AAMI/ISO validation protocol in adults and can be recommended for home BP measurements.The Omron HEM-7600T BP monitor fulfilled the requirements of the ANSI/AAMI/ISO validation protocol in adults and can be recommended for home BP measurements. Patients with masked hypertension have a higher incidence of target organ damage, including increased left ventricular mass and carotid atherosclerosis and cardiovascular events when compared with normotensive patients. GSK650394 The adverse cardiovascular risks are even greater in patients already taking antihypertensive medication. To identify the prevalence and clinical characteristics of masked hypertension in a large multicenter Brazilian sample that underwent office and home blood pressure monitoring. This was an observational cross-sectional analytical study based on secondary data from the teleMRPA online platform, which included 32 cities from 15 states in the five regions of Brazil. The database included 3704 outpatient participants with office blood pressure <140/90 mmHg who performed home blood pressure monitoring for diagnostic investigation (diagnosis group; n = 1819) or treatment (treatment group; n = 1885) of hypertension in 2018. The prevalence of masked hypertension was 18.0% in the whole ss already using antihypertensive medication.As the landscape of melanomagenesis becomes better refined through increasingly detailed schema grounded in distinct clinicopathologic-molecular pathways, the stepwise process and variations of molecular nevogenesis have largely remained elusive. Herein, we present a series of 8 melanocytic nevi in patients ranging from 40 to 74 years of age (median 59.5 y), which demonstrated a reproducible constellation of histomorphologic features as well as a copy number gain of the long arm of chromosome 15 (15q). The most characteristic histologic feature was sclerosis with maturation at the base of the lesion. All cases demonstrated a dome-shaped configuration and epidermal acanthosis with hyperpigmentation. However, the cytologic features ranged in their appearances from that of a banal nevus with ovoid nuclei, inconspicuous nucleoli, and minimal cytoplasm to enlarged, epithelioid forms with central nucleoli and abundant cytoplasm. No lesions showed staining with BRAF V600E or NRAS Q61R immunohistochemistry. Single-nucleotide polymorphism-based chromosome microarray analysis revealed a monoaberrant 15q gain in all cases.