The chewing trajectory in the dynamic analysis of dental prosthesis is always defined as a two-segmental straight polyline without enough consideration about chewing force and motion laws. The study was aimed to design a realistic human chewing trajectory for the dynamic analysis based on force and motion planning methods. The all-ceramic crown restored in the mandibular first molar was selected as the representative prosthesis. Firstly, a dynamic model containing two molar components and one flat food component was built, and an approximate chewing plane was predefined. According to the desired forces (25 N, 150 N and 25 N), three force planning points were calculated by using tentative trajectories. The motion planning was then executed based on four-segment cubic spline model. Finally, the new trajectory was re-imported into the dynamic model as the displacement load for evaluating its stress influence. The maximum lateral velocity was 26.81 mm/s. Besides, the forces in the three force planning points were 14.11 N, 126.75 N and 13.56 N. The overall repetition rate of chewing force was 77.21%. The force and stress profiles were similar to the sine curve on the whole. The maximum dynamic stress of the crown prosthesis was 398.5 MPa. The motion law was effectively brought into the chewing trajectory to introduce the dynamic effect. The global force performance was acceptable, and the force profile was more realistic than the traditional chewing trajectory. The additional reliable characteristic feature of the stress distribution of the dental prosthesis was observed.The motion law was effectively brought into the chewing trajectory to introduce the dynamic effect. The global force performance was acceptable, and the force profile was more realistic than the traditional chewing trajectory. The additional reliable characteristic feature of the stress distribution of the dental prosthesis was observed. The aim of this paper was to evaluate the effects of breathing retraining with chest wall mobilization on the onset of accessory breathing muscle recruitment and respiratory reserve in individuals with chronic neck pain. Thirty-two participants with non-specific chronic neck pain were randomly assigned into intervention and control groups. The intervention group received 30 minutes of breathing retraining with chest wall mobilization and the control group was assigned to rest for 30 minutes. Electromyography (EMG) of upper trapezius (UT), scalene (SC), and sternocleidomastoid (SCM) muscles were recorded during respiratory excursions by cycling for 12 minutes. Measurement of maximum voluntary ventilation (MVV), chest expansion, and pain intensity were taken during normal breathing. The immediate effects within each group and between two groups were analyzed. Significant improvement in respiratory reserve was observed in the intervention group compared to control group through prolonged EMG onset of accessory breathing muscles. Selleckchem Atuzabrutinib Moreover, increase of MVV, chest expansion and decrease in pain intensity were observed. This research suggests that breathing patterns and chest expansion should be considered within the physical assessment of breathing retraining, and that chest wall mobilization offers clinically important improvements in patients with chronic neck pain.This research suggests that breathing patterns and chest expansion should be considered within the physical assessment of breathing retraining, and that chest wall mobilization offers clinically important improvements in patients with chronic neck pain. The purpose of the study was presentation of modern bioengineering technology in order to help people with severe disabilities. Bioengineering industry can offer severely disabled people several devices in order to enable them to take part in the competition different than Paralympics. The first international competition for people with disabilities supported by modern assistive technology, such as sensors, motors, displays were allowed to compete in Cybathlon held in Zürich in 2016. About 70 athletes and their teams from 25 countries appeared at the event. There were six disciplines (races) 1) Powered Arms (Upper Extremities) Prostheses Race, 2) Powered Legs (Lower Extremities) Prostheses Race, 3) Powered Wheelchair Race, 4) Powered Exoskeleton Race, 5) Functional Electrical Stimulation Bike Race, 6) Brain-Computer Interface Race. About a quarter of the teams represented industry and the rest represented university laboratories. The competition was a success. The organisers have decided for it to be organized every four years, just like the Olympic Games for able bodied competitors. The main inventor of the event professor Robert Riener from Zürich Polytechnic (ETHZ) said assistive technology should a) be user-friendly b) to function well, c) be affordable, d) to be used within the barrier-free environment.The competition was a success. The organisers have decided for it to be organized every four years, just like the Olympic Games for able bodied competitors. The main inventor of the event professor Robert Riener from Zürich Polytechnic (ETHZ) said assistive technology should a) be user-friendly b) to function well, c) be affordable, d) to be used within the barrier-free environment. Bone is a hierarchical material that can be characterized from the microscale to macroscale. Multiscale models make it possible to study bone remodeling, inducing bone adaptation by using information of bone multiple scales. This work proposes a computationally efficient homogenization methodology useful for multiscale analysis. This technique is capable to define the homogenized microscale mechanical properties of the trabecular bone highly heterogeneous medium. In this work, a morphology- based fabric tensor and a set of anisotropic phenomenological laws for bone tissue was used, in order to define the bone micro-scale mechanical properties. To validate the developed methodology, several examples were performed in order to analyze its numerical behavior. Thus, trabecular bone and fabricated benchmarks patches (representing special cases of trabecular bone morphologies) were analyzed under compression. The results show that the developed technique is robust and capable to provide a consistent material homogenization, indicating that the homogeneous models were capable to accurately reproduce the micro-scale patch mechanical behavior.