Tuberculosis remains one of the most common infectious diseases. Miliary presentation is a rare and possibly lethal form, resulting from massive lymphohaematogenous dissemination of Mycobacterium tuberculosis bacilli. The authors describe the case of a 47-year-old immunocompetent woman, diagnosed with miliary tuberculosis, with both lung and central nervous system involvement, who showed total recovery after starting anti-tuberculous drugs. The atypical neutrophilic-predominant pleocytosis and negative cerebrospinal fluid microbiological results made the diagnosis even more challenging. Since prognosis largely depends on timely treatment, recognition and prompt diagnosis is important. Thus, clinicians should be aware and treatment should be initiated as soon as the diagnosis is suspected. Cerebrospinal fluid (CSF) characteristics in central nervous system tuberculosis (CNS TB) are variable and may even be normal. see more Typical CSF findings include lymphocytic-predominant pleocytosis, although neutrophilic predominance may occur. CSF microbiological testing for has low sensitivity, so a negative test does not eliminate the diagnosis.Cerebral magnetic resonance imaging is usually the test of choice, given its superiority in CNS TB diagnosis over computed tomography (CT), which can be normal.Chest x-ray may appear normal and miss miliary TB, which however a CT scan can identify.Cerebrospinal fluid (CSF) characteristics in central nervous system tuberculosis (CNS TB) are variable and may even be normal. Typical CSF findings include lymphocytic-predominant pleocytosis, although neutrophilic predominance may occur. CSF microbiological testing for Mycobacterium tuberculosis has low sensitivity, so a negative test does not eliminate the diagnosis.Cerebral magnetic resonance imaging is usually the test of choice, given its superiority in CNS TB diagnosis over computed tomography (CT), which can be normal.Chest x-ray may appear normal and miss miliary TB, which however a CT scan can identify. Ischaemic stroke can be classified according to its aetiology. In cryptogenic stroke, Lambl's excrescences should be considered since they can only be detected through transesophageal echocardiography (TEE), which is not routinely performed. The authors report the case of a 63-year-old Caucasian man with two ischaemic cerebral events associated with the presence of Lambl's excrescences in the aortic valve detected with TEE. Switching antiaggregant therapy to anticoagulant therapy allowed the patient to remain asymptomatic throughout a 3-year follow-up. The lack of protocols for the management of cryptogenic stroke results in a delay in the identification of less frequent causes of stroke, leading to recurrent vascular events, morbidity and loss of functionality. The authors describe a patient who experienced multiple cerebral ischaemic events until the correct diagnosis was made. Lambl's excrescences are a considered a rare cause of embolic stroke, probably because they are underdiagnosed.The pathophysiology is not fully understood, making therapeutic decisions difficult.Early recognition and management of this structural valve disease can prevent life-threatening complications.Lambl's excrescences are a considered a rare cause of embolic stroke, probably because they are underdiagnosed.The pathophysiology is not fully understood, making therapeutic decisions difficult.Early recognition and management of this structural valve disease can prevent life-threatening complications. To present a rare case of propofol-induced hepatitis. A 59-year old man was referred to our department because of suspicion of toxic hepatitis after propofol anaesthesia for endoscopic colonoscopy. The patient had jaundice, increased transaminases demonstrating liver necrosis, and liver stiffness of 18 kPa. Liver biopsy revealed bridging necrosis and initial post-collapse fibrosis. Following therapy with steroids and N-acetyl cysteine, the patient was discharged on the seventh day after admission in good general condition. Although propofol is considered safe, it can cause acute hepatitis, the seventh published case of which is reported here. Importantly, treatment with N-acetyl cysteine, a radical scavenger, but especially with steroids resulted in hepatic improvement. Drug-induced hepatitis is a severe illness caused by a large variety of agents, including many considered safe.It can occur in the absence of predisposing liver abnormality or disease.If the condition is correctly identified, clinical and laboratory abnormalities can be reversed with appropriate treatment.Drug-induced hepatitis is a severe illness caused by a large variety of agents, including many considered safe.It can occur in the absence of predisposing liver abnormality or disease.If the condition is correctly identified, clinical and laboratory abnormalities can be reversed with appropriate treatment.Right heart thrombi are detected in approximately 4% of patients with pulmonary embolism. The associated mortality is high, but the optimal strategy remains controversial. We report a case of a large mobile right heart thrombus, complicated by embolism of the right pulmonary artery, which was successfully treated with half-dose alteplase. We briefly review the literature and discuss the therapeutic options, focusing on the advantages of thrombolysis. Mobile right heart thrombi require rapid therapeutic choices between surgical thrombectomy and thrombolysis.Half-dose alteplase may be effective, even in the presence of an extensive thrombus burden.Mobile right heart thrombi require rapid therapeutic choices between surgical thrombectomy and thrombolysis.Half-dose alteplase may be effective, even in the presence of an extensive thrombus burden.First described by the French surgeon Maurice Morel-Lavallee in 1853, Morel-Lavallee syndrome (MLS) is a serolymphatic effusion resulting from tangential injury to richly vascularized tissues. The imaging characteristics may be variable over time due to lesion progression and the eventual organization of a fibrous capsule. We report a case of extensive MLS in the lower leg of a 12-year-old child. We discuss the ultrasound and magnetic resonance imaging findings and describe the differential diagnoses. The diagnosis of Morel-Lavallee syndrome is based on clinical examination and imaging techniques.The post-traumatic context is important for diagnosis.Morphological aspects depend on lesion progression and the eventual organization of a fibrous capsule.The diagnosis of Morel-Lavallee syndrome is based on clinical examination and imaging techniques.The post-traumatic context is important for diagnosis.Morphological aspects depend on lesion progression and the eventual organization of a fibrous capsule.