Rodrigues, GM, Machado, S, Faria Vieira, LA, Ramalho de Oliveira, BR, Jesus Abreu, MA, Marquez, G, Maranhão Neto, GA, and Lattari, E. Effects of anodal transcranial direct current stimulation on training volume and pleasure responses in the back squat exercise following a bench press. J Strength Cond Res XX(X) 000-000, 2021-This study aimed to investigate the effects of anodal transcranial direct current stimulation (a-tDCS) on volume-load and pleasure responses in a back squat following a bench press. Twelve male subjects advanced in resistance training (RT) (age, 25.5 ± 4.4 years) completed 2 experimental trials in a counterbalanced crossover design a-tDCS and sham conditions. The stimulus was applied over the left dorsolateral prefrontal cortex for 20 minutes using a 2-mA current intensity in a-tDCS condition and 1 minute of active stimulus in the sham condition. Immediately after stimulation, subjects performed the bench press followed by the back squat. The exercise protocol consisted of 3 sets of maxioad was higher in the a-tDCS condition than in the sham condition for both exercises (p = 0.02), with large effect for the back squat (p = 0.045; d = 0.96). The higher volume-load was obtained by increasing the number of repetitions across all sets for the bench press (p ≤ 0.0001) and only in the first set for the back squat (p = 0.01). The circumplex model analysis showed a higher pleasure in the bench press and a tendency toward a higher pleasure in the a-tDCS condition. Anodal tDCS may be used as an ergogenic resource for increasing the back squat volume after performing the bench press in resistance-trained male subjects. Howarth, DJ, Cohen, DD, McLean, BD, and Coutts, AJ. Establishing the noise interday ecological reliability of countermovement jump variables in professional rugby union players. J Strength Cond Res XX(X) 000-000, 2021-The purpose of this study was to examine the interday "ecological" reliability of a wide range of ground reaction force-derived countermovement jump (CMJ) variables. Thirty-six male, professional rugby union players performed 3 CMJs on 4 separate days over an 8-day period during the first week of preseason. Selleckchem CB-5083 We calculated reliability for 86 CMJ variables across 5 interday combinations using 2 criteria mean output across 3 jump trials (Mean3) and single output from the highest jump (BestJH). Interday coefficient of variation (CV) of the 86 variables in each CMJ phase, for Mean3 and BestJH, respectively, ranged between concentric = 2-11% and 2-13%; eccentric = 1-45% and 1-107%; and landing = 4-32% and 6-45%. Mean3 interday CV was lower in all 86 variables across every interday combination, comparsis provides reference reliability for a wide range of CMJ variables. However, we recommend that practitioners assess reliability in their athletes, as it is likely to be environment, protocol, and cohort specific. Kotani, Y, Lake, J, Guppy, SN, Poon, W, Nosaka, K, Hori, N, and Haff, GG. The reliability of the squat jump force-velocity and load-velocity profiles. J Strength Cond Res XX(X) 000-000, 2021-The purpose of this study was to investigate the between-session reliability of the squat jump force-velocity (FV) and load-velocity (LV) profiles. Eighteen subjects (age = 28.1 ± 4.8 years; height = 1.7 ± 9.7; body mass = 74.7 ± 12.8) who could back squat >1.5 times body mass participated in this study. Each subject completed a familiarization session, followed by 2 experimental sessions each separated by 72 hours. Subjects performed a series of squat jumps on a force plate against external loads between 0 and 100% of their body mass in a quasi-randomized block order. Intraclass correlation coefficient (ICC) and coefficient of variation (CV) were used to examine the between-session reliability. Peak velocity (PV) and mean velocity (MV) at each load were highly reliable (ICC >0.80, CV% <7.41, SEM <0.13 m·s-10.34-0.92, CV% = 11.9-26.3). When mean and relative mean forces were used to create FV profiles, there was poor to good reliability (ICC = 0.03-0.85, CV% = 18.1-39.4). When the LV profile was calculated with PV (ICC = 0.60-0.90, CV% = 7.9-16.9) or MV (ICC = 0.49-0.91, CV% = 11.1-23.4), there was poor to excellent reliability. There was no time effect found between sessions for both FV and LV profiles. The squat jump FV and LV profiles established with a force plate are not reliable. Therefore, these profiles are not recommended to be used to inform programming decisions. Development and functions of hematopoietic stem cells (HSC) are regulated by multiple cellular components of the hematopoietic niche. Here we review the recent advances in studying the role of three such components -- osteoblasts, osteomacs, and megakaryocytes and how they interact with each other in the hematopoietic niche to regulate HSC. Recent advances in transgenic mice models, scRNA-seq, transcriptome profile, proteomics, and live animal imaging have revealed the location of HSC within the bone and signaling molecules required for the maintenance of the niche. Interaction between megakaryocytes, osteoblasts and osteomacs enhances hematopoietic stem and progenitor cells (HSPC) function. Studies also revealed the niche as a dynamic entity that undergoes cellular and molecular changes in response to stress. Aging, which results in reduced HSC function, is associated with a decrease in endosteal niches and osteomacs as well as reduced HSC--megakaryocyte interactions. Novel approaches to study the cellular components of the niche and their interactions to regulate HSC development and functions provided key insights about molecules involved in the maintenance of the hematopoietic system. Furthermore, these studies began to build a more comprehensive model of cellular interactions and dynamics in the hematopoietic niche.Novel approaches to study the cellular components of the niche and their interactions to regulate HSC development and functions provided key insights about molecules involved in the maintenance of the hematopoietic system. Furthermore, these studies began to build a more comprehensive model of cellular interactions and dynamics in the hematopoietic niche.