7%, 80.5%, and 87.1% at 6, 12, 24, and 36 months, respectively. Cox proportional hazards modeling revealed that adalimumab was associated with a higher risk of at least one suboptimal response (hazard ratio [HR], 1.29; 95% confidence interval [CI], 1.13 to 1.48), dose escalation (HR, 4.35; 95% CI, 2.97 to 6.38) and discontinuation (HR, 1.25; 95% CI, 1.03 to 1.52) than infliximab. Golimumab was associated with a higher risk of switching to other biologics than infliximab (HR, 1.78; 95% CI, 1.21 to 2.60). More than half of Korean UC patients had suboptimal responses to anti-TNF agents within 1 year. UC patients treated with infliximab might be less prone to suboptimal responses than those treated with adalimumab or golimumab.More than half of Korean UC patients had suboptimal responses to anti-TNF agents within 1 year. UC patients treated with infliximab might be less prone to suboptimal responses than those treated with adalimumab or golimumab. Low-income adolescents' physical activity (PA) levels fall below current recommendations. Perceived barriers to physical activity (PBPA) are likely significant predictors of PA levels; however, valid and reliable measures to assess PA barriers are lacking. This manuscript describes the development of the PBPA Survey for Low-Income Adolescents. A mixed-method approach was used. Items identified from the literature and revised for clarity and appropriateness (postcognitive interviews) were assessed for test-retest reliability with 74 adolescents using intraclass correlation coefficient. Items demonstrating low intraclass correlation coefficients or floor effects were removed. Both exploratory factor analysis and confirmatory factor analysis analyses (n = 1914 low-income teens) were used to finalize the scale; internal consistency was assessed by Cronbach's alpha. Concurrent validity was established by correlating the PBPA with the PA questionnaire for adolescents using a Spearman correlation. The exploratory factor analysis yielded a 38-item, 7-factor solution, which was cross-validated by confirmatory factor analysis (comparative-fit index, nonnormed fit index = .90). The scale's Cronbach's alpha was .94, with subscales ranging from .70 to .88. The PBPA Survey for Low-Income Adolescents' concurrent validity was supported by a negative PA questionnaire for adolescents' correlation values. The PBPA Survey for Low-Income Adolescents can be used to better understand the relationship between PBPA among low-income teens. Further research is warranted to validate the scale with other adolescent subgroups.The PBPA Survey for Low-Income Adolescents can be used to better understand the relationship between PBPA among low-income teens. Further research is warranted to validate the scale with other adolescent subgroups.Justifications for access to physical activity for people who experience disability tend to focus on the health benefits associated with a medical model of disability. The result is often programs that are segregated and impairment-focused, with limited access to integrated settings that are also potentially inclusive. In this instrumental case study, the authors engaged 20 participants with and without impairment from an adult integrated indoor cycling program to explore what contributed to meaningful and inclusive experiences in this setting. find more Data were generated through semistructured interviews and reflective notes. Thematic analysis led to three themes (a) "just going to a spin class" (b) "seamless"? and (c) "deliberate community." Using a relational ethics framework, the findings are discussed with regard to their potential to inform the development of integrated and inclusive physical activity programs, with emphasis on program structure and instructor reflexivity and training.The authors' purpose was to examine the factors associated with penalty outcomes of male elite goalball. A total of 122 video-recorded matches from two Paralympic Games (i.e., 2012 and 2016) and the 2014 Goalball World Championship were assessed using notational analysis. Individual (n = 2), situational (n = 4), and performance variables (n = 7) were analyzed with good strength of agreement for intra- and interrater kappa index values. Their results showed that penalties play a very important role in the final score, composing around 25% of total goals in elite goalball matches. Winners were awarded on average with 62% of penalties and had 66% effectiveness compared with losers (31% and 53%) or drawers (8% and 52%). Based on the authors' findings, penalty takers should direct their throws at specific target sectors on the court, which could increase their rate of success to over 80%.In this study, the effects of an exercise therapy comprising yoga exercises and medial-thrust gait (YogaMT) on lower-extremity kinetics, pain, and function in patients with medial knee osteoarthritis were investigated. Fifty-nine patients were randomly allocated to three treatment groups (a) the YogaMT group practiced yoga exercises and medial thrust gait, (b) the knee-strengthening group performed quadriceps- and hamstring-strengthening exercises, and (c) the treadmill walking group practiced normal treadmill walking in 12 supervised sessions. The adduction and flexion moments of the hip, knee, and ankle; pain intensity; and 2-min walking test were assessed before and after treatment and at 1-month follow-up. The YogaMT group experienced a significant reduction in knee adduction moment. All groups showed significant improvement in pain and function. The YogaMT may reduce medial knee load in patients with knee osteoarthritis in the short term. A larger clinical trial is required to investigate the long-term outcomes of this intervention. The prevalence of childhood obesity is higher in economically and socially deprived areas. Higher levels of physical activity reduce the risk of excessive weight gain in youth, and research has focused on environmental factors associated with children's physical activity, though the term "physical activity desert" has not come into wide use. This exploratory study operationalized the term "physical activity desert" and tested the hypothesis that children living in physical activity deserts would be less physically active than children who do not. A cross-sectional study design was applied with 992 fifth-grade students who had provided objectively measured physical activity data. Five of 12 possible elements of the built environment were selected as descriptors of physical activity deserts, including no commercial facilities, no parks, low play spaces, no cohesion, and the presence of incivilities. Univariate and multivariate analyses showed that only the absence of parks was associated with less physical activity in children.