AIM This article introduces a new milling unit (Cerec Primemill, Dentsply Sirona). Clinical cases show how this new milling unit functions to improve the overall workflow of single-visit chairside dentistry. MATERIALS AND METHODS The unit has a touchscreen that guides the user through the process of setting up the manufacturing job. This process, along with the pretouch process, is completed prior to the procedure. In addition to the guided workflow, the milling unit has a new block scanner and a radio-frequency identification (RFID) reader for bur identification/monitoring. It also has new milling tools and manufacturing algorithms and uses a unique parallel milling strategy with zirconia and a novel grinding strategy with glass-ceramic. RESULTS The optimized tool geometries and manufacturing algorithms along with new mechanical and electronic components allow for an improvement in quality and speed.BACKGROUND Accurate implant placement in the bone is key to successful implant treatment. Once inserted, it can be difficult to correct the orientation of the implant axis, especially of a one-piece implant. Prosthetic-driven digital implant planning in combination with fully guided implant surgery can offer additional safety in such cases. CASE PRESENTATION The patient presented with a wide, edentulous interdental space extending from sites 13 to 16, which was to be restored with three one-piece zirconia implants supporting a zirconia fixed partial denture comprizing a cantilever to the mesial aspect. Digital planning based on DICOM (Digital Imaging and Communications in Medicine) and intraoral surface data was performed to ensure optimal positioning. Guided implant placement was executed using a contra-angle handpiece with special attachments and a compatible, sleeveless drill guide. Impressions of the implants for the final restoration were acquired using an intraoral scanner. Reflection-related errors werion when acquiring impressions for implants of this type in the future.AIM An orthodontic treatment is described that combines the use of clear aligners and computer-guided piezocision to overcome the drawbacks of traditional corticotomy in accelerating orthodontic tooth movement. The relapse at the 2-year follow-up was also evaluated. MATERIALS AND METHODS A 13-year-old male patient was selected and treated due to a molar Class II malocclusion with moderate dental crowding. Treatment time, oral health-related quality of life (OHRQoL), and periodontal indexes were assessed. To reduce the treatment time, computer-guided piezocision was utilized to perform flapless interproximal corticotomy cuts through the depth of the cortical bone. The orthodontic therapy using clear aligners began on the same day as the surgery. RESULTS The overall duration of the therapy was 6 months. There was an improvement in the periodontal indexes at the end of the therapy. An aggravation of OHRQoL only occurred for 3 days after surgery. The 2-year follow-up evaluation showed a relapse of 0.2 mm on the maxillary left lateral incisor and 0.25 mm on the mandibular right lateral incisor. CONCLUSION The present case report describes the advantages of a combination of computer-guided piezocision and clear aligners to treat a Class II malocclusion with moderate crowding.AIM Evaluation of appropriate models for computer-aided design/computer-aided manufacturing (CAD/CAM) in vitro studies by investigation of different model materials regarding suitability for intraoral scanners and dimensional stability. MATERIALS AND METHODS A typodont model was prepared to accommodate a 10-unit prosthesis. The model was duplicated using six different materials class IV die stone (DS), cobalt-chrome molybdenum (CoCrMo), epoxy resin (EPOX), polyurethane (PU), titanium (TI), and zirconia (ZI). An intraoral scanner was used to obtain three scans of each model. PR-619 chemical structure Reference datasets were generated using micro-computed tomography (micro-CT). The first scan was compared with the corresponding reference micro-CT dataset to assess its trueness. The precision was measured by comparing all scans within one test group. For the evaluation of dimensional stability, micro-CT was used to generate three-dimensional (3D) datasets of the models at different time intervals over a 6-week period. The models were kept under constant conditions during the study. All datasets were analyzed with software that determined the deviation of two datasets by alignment using a best-fit algorithm. RESULTS The criterion of trueness was fulfilled by CoCrMo, EPOX, PU, and the typodont model. Scans of CoCrMo and ZI showed the best precision. PU and the typodont model did not meet the requirement of dimensional stability, whereas EPOX and gypsum were stable only for a period of 10 days. CONCLUSION The CoCrMo model was the only one that met all the criteria for an appropriate model for CAD/CAM in vitro studies. The other investigated materials either lacked dimensional stability or could not be scanned accurately and reproducibly.BACKGROUND The Dental Motion Decoder system (DMS-System) is a medical device based on magnetic field technology that records mandible movements. The data can be used to program an articulator or can be directly processed over a computer-aided design (CAD) interface. The present study aimed to assess the reproducibility of this system in vitro and in vivo. MATERIAL AND METHODS Protrusive and laterotrusive movements were simulated in vitro using an articulator (SAM SE) (Group M) and in vivo (Group P) on one test individual. Measurements were carried out in two ways 1) Measurements were taken after initializing and referencing the system using the reference points (RPs) once, followed by 30 protrusive and laterotrusive movements (M1 and P1); and 2) Thirty individual measurements were recorded using the RPs before each measurement (M2 and P2). Values for the sagittal condylar path inclination angle (sCPIA) and the Bennett angle (BA) were exported and analyzed. The reproducibility of the system was evaluated using the standard deviations (SDs) of the measurement series (sCPIA and BA for M1, M2, P1, and P2). RESULTS In vitro tests M1 (SD sCPIA = 0.08 degrees; BA = 0.06 degrees) and M2 (SD sCPIA = 0.26 degrees; BA = 0.11 degrees) showed significantly higher reproducibility (P less then 0.001) compared with the in vivo measurements P1 (SD sCPIA = 0.61 degrees; BA = 0.45 degrees) and P2 (SD sCPIA = 1.4 degrees; BA = 0.65 degrees). CONCLUSION Within the limitations of the present study, the deviation in vitro, representing the reproducibility of the DMD-System, is smaller than the biologic variance observed in vivo. Therefore, reliable measurements under clinical conditions can be assumed.