Moreover, to find out the optimal hyperparameters of the base estimators, a swarm intelligent optimization algorithm, pigeon-inspired optimization (PIO), is employed. The proposed method is tested on a semiphysical platform of the CRH2 traction system in CRRC Zhuzhou Locomotive Company Ltd. The results show that the fault diagnosis rate of the proposed scheme is over 96%.This article presents a new command-filtered composite adaptive neural control scheme for uncertain nonlinear systems. Compared with existing works, this approach focuses on achieving finite-time convergent composite adaptive control for the higher-order nonlinear system with unknown nonlinearities, parameter uncertainties, and external disturbances. First, radial basis function neural networks (NNs) are utilized to approximate the unknown functions of the considered uncertain nonlinear system. By constructing the prediction errors from the serial-parallel nonsmooth estimation models, the prediction errors and the tracking errors are fused to update the weights of the NNs. Afterward, the composite adaptive neural backstepping control scheme is proposed via nonsmooth command filter and adaptive disturbance estimation techniques. The proposed control scheme ensures that high-precision tracking performances and NN approximation performances can be achieved simultaneously. Meanwhile, it can avoid the singularity problem in the finite-time backstepping framework. Moreover, it is proved that all signals in the closed-loop control system can be convergent in finite time. Finally, simulation results are given to illustrate the effectiveness of the proposed control scheme.This article presents concurrent associative memories with synaptic delays useful for processing sequences of real vectors. Associative memories with synaptic delays were introduced by the authors for symbolic sequential inputs and demonstrated several advantages over other sequential memories. They were easy to organize and train. It was demonstrated that they were more robust than long short-term memories in recognition of damaged sequences. The associative memories can be applied in combination with deep neural networks to solve such symbol grounding problems, such as speech recognition, and support sequential memories triggered by sensory inputs. Several practical considerations for developed memories were discussed and illustrated. A continuous speech database was used to compare the developed method with LSTM memories. Tests demonstrated that the developed approach is more robust in recognition of speech sequences, particularly when the test sequences are damaged.In the area of biomedical signal monitoring, wearable electronics represents a dynamically growing field with a significant impact on the market of commercial products of biomedical signal monitoring and acquisition, as well as consumer electronic for vital functions monitoring. Since the electrodes are perceived as one of the most important part of the biomedical signal monitoring, they have been one of the most frequent subjects in the research community. Electronic textile (e-textile), also called smart textile represents a modern trend in the wearable electronics, integrating of functional materials with common clothing with the goal to realize the devices, which include sensors, antennas, energy harvesters and advanced textiles for self-cooling and heating. The area of textile electrodes and e-textile is perceived as a multidisciplinary field, integrating material engineering, chemistry, and biomedical engineering. In this review, we provide a comprehensive view on this area. This multidisciplinary review integrates the e-textile characteristics, materials and manufacturing of the textile electrodes, noise influence on the e-textiles performance, and mainly applications of the textile electrodes for biomedical signal monitoring and acquisition, including pressure sensors, electrocardiography, electromyography, electroencephalography and electrooculography monitoring.Parallelization in Python integrates Message Passing Interface via the mpi4py module. Since mpi4py does not support parallelization of objects greater than 231 bytes, we developed BigMPI4py, a Python module that wraps mpi4py, supporting object sizes beyond this boundary. BigMPI4py automatically determines the optimal object distribution strategy, and uses vectorized methods, achieving higher parallelization efficiency. BigMPI4py facilitates the implementation of Python for Big Data applications in multicore workstations and High Performance Computer systems. We use BigMPI4py to speed-up the search for germ line specific de novo DNA methylated/unmethylated motifs from the 59 whole genome bisulfite sequencing DNA methylation samples from 27 human tissues of the ENCODE project. We developed a parallel implementation of the Kruskall-Wallis test to find CpGs with differential methylation across germ layers. The parallel evaluation of the significance of 55 million CpG achieved a 22x speedup with 25 cores allowing us an efficient identification of a set of hypermethylated genes in ectoderm and mesoderm-related tissues, and another set in endoderm-related tissues and finally, the discovery of germ layer specific DNA demethylation motifs. Our results point out that DNA methylation signal provide a higher degree of information for the demethylated state than for the methylated state.We propose a procedure for modeling a phenotype using QTLs which estimate the additive and dominance effects of genotypes and epistasis. The estimation of the model is implemented through a Bayesian approach which uses the data-driven reversible jump (DDRJ) for multiple QTL mapping and model selection. GNE-049 We compare the DDRJ's performance with the usual reversible jump (RJ), QTLBim, multiple interval mapping (MIM) and LASSO using real and simulated data sets. The DDRJ outperforms the available methods to estimate the number of QTLs in epistatic models and it identifies their locations in the genome, without increasing the number of false-positive QTLs in the considered data. Since QTL mapping is a regression model involving complex non-observable variables and their interactions, the model selection procedure proposed here is also useful in other areas of research. The application for identifying main and epistatic relevant QTLs to systolic blood pressure after salt intervention is our main motivation.