Multifunctional polymer composites with anisotropic properties are attracting interest as they fulfil the growing demand of multitasking materials. In this work, anisotropic polymer composites have been fabricated by combining the layer-by-layer (LBL) filtration method with the alternative assembling of carbon nanotubes (CNTs) and hexagonal boron nitride flakes (hBN) on natural rubber latex particles (NR). The layered composites exhibit anisotropic thermal and electrical conductivities, which are tailored through the layer formulations. The best composite consists of four layers of NR modified with 8 phr (parts per Hundred Rubber) CNTs (∼7.4 wt%) and four alternate layers with 12 phr hBN (∼10.7 wt%). The composites exhibit an electromagnetic interference (EMI) shielding effectiveness of 22.41 ± 0.14 dB mm-1 at 10.3 GHz and a thermal conductivity equal to 0.25 W m-1 K-1. Furthermore, when the layered composite is used as an electrical thermal heater the surface reaches a stable temperature of ∼103 °C in approx. 2 min, with an input bias of 2.5 V.Electron transfer processes between proteins are vital in many biological systems. Yet, the role of the solvent in influencing these redox reactions remains largely unknown. Saracatinib order In this study, terahertz-time domain spectroscopy (THz-TDS) is used to probe the collective hydration dynamics of flavoenzyme ferredoxin-NADP+-reductase (FNR), electron transfer protein ferredoxin-1 (PetF), and the transient complex that results from their interaction. Results reveal changes in the sub-picosecond hydration dynamics that are dependent upon the surface electrostatic properties of the individual proteins and the transient complex. Retarded solvent dynamics of 8-9 ps are observed for FNR, PetF, and the FNRPetF transient complex. Binding of the FNRPetF complex to the substrate NADP+ results in bulk-like solvent dynamics of 7 ps, showing that formation of the ternary complex is entropically favored. Our THz measurements reveal that the electrostatic interaction of the protein surface with water results in charge sensitive changes in the solvent dynamics. Complex formation between the positively charged FNRNADP+ pre-complex and the negatively charged PetF is not only entropically favored, but in addition the solvent reorganization into more bulk-like water assists the molecular recognition process. The change in hydration dynamics observed here suggests that the interaction with the solvent plays a significant role in mediating electron transfer processes between proteins.Direct C-H functionalization is very important in the late-stage functionalization of drug molecules. In this context, visible light promoted transformations have emerged as a green strategy for C-H functionalization compared to the conventional strategy. Various methodologies have been developed for the C-H functionalization of different bioactive heterocycles employing this visible light photocatalysis in the presence of either transition metal photocatalysts or organophotoredox catalysts and even in the absence of any photocatalyst. The focus of this review is the demonstration of the efficiency of visible light photocatalysis in the direct C-H functionalizations of pharmacologically active imidazo[1,2-a]pyridines and other related imidazoheterocycles.Correction for 'An NIR-responsive mesoporous silica nanosystem for synergetic photothermal-immunoenhancement therapy of hepatocellular carcinoma' by Han Yang et al., J. Mater. Chem. B, 2020, 8, 251-259.Super-resolution optical fluctuation imaging (SOFI) produces fast, background-free, super-resolved images by analyzing the temporal fluorescence fluctuations of independent emitters. With sufficient brightness and fluctuations, a higher order of image processing affords a higher resolution and in principle the resolution enhancement is unbounded. However, it is practically challenging to find suitable probes for high-order SOFI. Herein, we report two types of BODIPY-based polymer dots (Pdots) with narrow-band emissions, pronounced fluctuations, and prominent photostability, thus enabling high-order, dual-color SOFI nanoscopy. Single-particle and subcellular SOFI analysis reveals the superior performance of the BODIPY Pdots as compared to conventional streptavidin-conjugated Alexa dyes. In contrast with wide-field images, the spatial resolution (∼57 nm) was enhanced by ∼6.0-fold in 8th-order single-particle SOFI nanoscopy. A spatial resolution (61 nm) was obtained for single microtubules labeled by the BODIPY Pdots, while the majority of the subcellular structures were lost for those labeled by streptavidin-Alexa dyes in 8th-order SOFI. This work indicates the unprecedented performance of Pdot probes for multi-color subcellular SOFI applications.The elusive cis tautomer of free-base porphyrins has recently been isolated and structurally characterized in the form of a supramolecular complex. The question as to whether a suitable set of peripheral substituents might lead to a stable cis tautomer in the absence of supramolecular interactions, however, remains unanswered and is one we have attempted to address here by means of density functional theory calculations. The fact that many antipodally β-tetrasubstituted tetraphenylporphyrin derivatives exhibit localized central protons attached to the β-unsubstituted pyrrole rings led us to surmise that β-tetrasubstitution of adjacent pyrrole rings might lead to a porphyrin cis tautomer, an idea that proved fruitful. Indeed, for the "adjacently" substituted tetraphenylporphyrin derivative H2[adj-(CF3)4(CH3)4TPP], the global energy minimum proved to be a highly saddled cis tautomer, with the trans tautomer about 0.07 eV higher in energy. It is important to underscore, however, that the asymmetric β-substitution pattern is far from the only factor contributing to the stability of the cis tautomer for this porphyrin. A strongly saddled conformation resulting from meso-β steric interactions also helps alleviate the repulsion between the two central NH protons, thereby stabilizing the cis tautomer relative to the trans.Geometrical confinement plays an important role in generating novel molecular organization arising out of structural frustration and confinement-induced entropy loss. In the present study, we perform self-consistent mean-field theoretical calculations to examine a mixture of a diblock copolymer and polymer grafted nanoparticles confined in a cylindrical nanopore. The two-dimensional analysis is aimed at constructing the equilibrium nanostructures decorated with particles in an ordered manner. The rich variety of ordered mesophases of the diblock copolymer under confinement provide a template to achieve the self-assembly of nanoparticles in a selective domain. The localization behavior of nanoparticles under confinement is found to be qualitatively different from that in a bulk system. In particular, for the concentric lamellar phase the particles tend to localize predominantly in the region of greater curvature within the curved lamella. The incorporation of grafted nanoparticles also results in a transition in ordered phases.