All patients had undergone surgery previously and had received postoperative concurrent chemoradiotherapy. The 4 patients in this study were diagnosed with head and neck malignancies. The median follow-up period after the first course of BNCT was 15.1 months. After BNCT, 2 patients developed impending CBS, and 1 of them died. The remaining 3 patients survived until the last date of follow-up. Pre-BNCT carotid artery evaluation through computed tomography angiography and early intervention if necessary is crucial when treating patients with recurrent head and neck cancers by BNCT.Pre-BNCT carotid artery evaluation through computed tomography angiography and early intervention if necessary is crucial when treating patients with recurrent head and neck cancers by BNCT. Our previous study showed that carcinoembryonic antigen (CEA), squamous cell carcinoma antigen (SCC-Ag), and ferritin are significantly higher in patients with oral potentially malignant disorders (OPMDs including oral leukoplakia, oral erythroleukoplakia, and oral verrucous hyperplasia) than in healthy controls (HCs). Oral submucous fibrosis (OSF) is also recognized as an OPMD. This study evaluated whether these three serum tumor marker levels were also significantly higher in OSF patients than in HCs. The serum CEA, SCC-Ag, and ferritin levels in 41 OSF patients and 164 HCs were measured and compared. Patients with serum CEA level ≥3 ng/mL, SCC-Ag level ≥2 ng/mL, and ferritin level ≥250 ng/mL were scored as serum positive for CEA, SCC-Ag, and ferritin, respectively. We found significantly higher mean serum CEA, SCC-Ag, and ferritin levels in 41 OSF patients than in 164 HCs (all -values < 0.05). Moreover, 41 OSF patients had significantly higher serum positive rates of CEA (39.0%), SCC-Ag (19.5%), and ferritin (53.7%) than 164 HCs (all -values < 0.05). Of the 41 OSF patients, 26 (63.4%), 7 (17.1%), and 2 (4.9%) had serum positivities of one, two, or three tumor markers including CEA, SCC-Ag, and ferritin, respectively. There are significantly higher mean serum CEA, SCC-Ag, and ferritin levels and significantly higher serum positive rates of CEA, SCC-Ag, and ferritin in OSF patients than in HCs. The serum CEA, SCC-Ag, and ferritin levels may be served as tumor markers for evaluation of malignant potential of OSF lesions.There are significantly higher mean serum CEA, SCC-Ag, and ferritin levels and significantly higher serum positive rates of CEA, SCC-Ag, and ferritin in OSF patients than in HCs. The serum CEA, SCC-Ag, and ferritin levels may be served as tumor markers for evaluation of malignant potential of OSF lesions. Virtual microscopy has been used for teaching general and oral pathology laboratory course for more than 10 years. This study aimed to share the learning experience of an oral pathology laboratory course using either the virtual microscopy with digitalized virtual slides (virtual slide learning) or real microscopy using traditional glass slides (glass slide learning) among dental students. Thirty-eight undergraduate dental students who took the compulsory course entitled "oral pathology" in the School of Dentistry, National Taiwan University were included in this study. The questionnaires were filled and final test was taken by these students after finishing the teaching of oral pathology laboratory course using either virtual or glass slide learning. The data were collected and analyzed statistically. Our results showed a significantly higher acceptance rate (all -values < 0.001) and a significantly better histopathological diagnosis ability (  < 0.01) among dental students using the virtual sscopic images of the patients' specimens may be added in the patients' digital medical charts in addition to the images of computerized tomography, magnetic resonance imaging, and sonography in the future. Bio-Oss® collagen (BC) has been used in clinical applications for years but the ridge preservation property of BC remains controversial. There is no animal model accurately simulates the extraction socket in people. The aim of this study was to assess the ridge preservation of a novel extraction sockets with a thin buccal plate using BC. Two beagle dogs were used to assess the characterization of the novel extraction socket. The width and height of the socket were measured and biopsies of the socket were collected for histologic examination. Four beagle dogs were used to assess the ridge preservation property of BC. BC was placed in the socket and socket left untreated was set as control group (CT). Cone-beam computed tomography analysis, histological examination, and micro-CT analysis were used to evaluate the ridge preservation. The novel extraction socket had obvious larger volume with a markedly narrow buccal wall than mandible extraction sockets. At 12 weeks, the width of the crest of the alveolar ridge preservation ratios was 34% for the CT and 82% for the BC. BC group had larger socket volume compare to CT group. click here BC group had a significant higher bone density in the middle and apical areas of the alveolar bone. Socket placed with BC showed significantly less vertical bone loss compared with CT group. Extraction site with a significantly larger dimension and a very thin buccal plate was established. Extraction sockets filled with BC exhibit excellent maintenance of alveolar bone volume.Extraction site with a significantly larger dimension and a very thin buccal plate was established. Extraction sockets filled with BC exhibit excellent maintenance of alveolar bone volume. Actinomycosis is sometimes associated with a radicular cyst (RC). This retrospective study evaluated the clinical and histopathological features of 6 RCs with actinomycosis (AM/RCs). The demographic data and clinicopathological features of 6 AM/RCs were collected and analyzed. The 6 AM/RCs were taken from 2 male and 4 female patients, and 3 were found in the maxilla and the other 3 in the mandible. The involved teeth included maxillary or mandibular incisors (2 cases) and maxillary or mandibular first and second molars (4 cases). The most common symptom was pain (5 cases) and the more frequent signs were sinus tract and pus discharge (4 cases). Microscopically, the actinomycotic colony presented as a mass with filamentous bacteria arranging in a sun-ray pattern at the periphery. The mean actinomycotic colony number was 7.7 ± 6.6 colonies per slide. Due to the severe inflammation in all 6 AM/RCs, the stratified squamous epithelial lining was completely abolished in 2 cases and partially destroyed in 4 cases with the residual epithelial lining varying from approximately 10%-50%.