About seller
Oxidative stress causes and drives many agonising inflammatory conditions, which cause disability, financial burden, and emotional stress. The current anti-inflammatory, analgesic, and antioxidant agents are associated with adverse effects, inaccessibility, high costs, and low efficacies, thereby warranting the need for alternatives, especially from natural sources. Lonchocarpus eriocalyx plant is traditionally used in Kenyan communities to treat various inflammatory and oxidative stress-associated diseases; however, its pharmacologic efficacy and safety have not been empirically validated, hence this study. The in vivo antiinflamatory and antinociceptive efficacy of the aqueous and methanolic stem bark extracts of L. eriocalyx were determined using the xylene-induced ear oedema, and the acetic acid-induced writhing techniques, respectively, in experimental mice. Also, in vitro antioxidant activities of the studied plant extracts were investigated using the Thiobarbituric acid test for lipid peroxidation, 1, . Further studies on the anti-inflammatory, antinociceptive and antioxidant mechanism(s) and isolation and characterisation of responsible compounds are encouraged to spur the development of affordable, accessible, safe, and efficacious drugs. Hemolacria is a rare condition that is characterized by the presence of blood in tears. It is a rare condition due to which insufficient literature and resources are present. Therefore, its prevalence and predilection for a specific gender, race or age remain uncertain. Hemolacria is one of the most alarming symptoms in ophthalmology, associated with multiple underlying etiologies and diseases. We report an unusual case of a 12-year-old female patient who experienced episodic bilateral bloody tears for 3 days, which was associated with epistaxis. The patient's condition was thoroughly evaluated, and all investigations were unremarkable. The patient was then referred to an ophthalmologist for evaluation, and a slit-lamp examination was also unremarkable. After performing all necessary investigations and taking various causes of hemolacria into account, the child was diagnosed as having idiopathic hemolacria. The patient and parent were appropriately counseled regarding the disease, and thereafter, the patidy tears were resolved spontaneously. Consumption patterns of people around the world have been tremendously affected due to the COVID-19 outbreak since December 2019. Previous studies validated the influence of both internal and external factors on consumer behaviour. However, due to the lack of empirical research, this study explored the influence of external factor such as COVID-19 on consumer purchase behaviour, economic and financial situation. In addition, the study investigated how crisis perception and consumption pattern vary due to demographic variables. A convenience sampling technique was used and a total of 340 responses were collected from three countries, e.g., Bangladesh (n = 129), India (n = 122), and Pakistan (n = 89) using a structured questionnaire. The respondents rated the items, collected from relevant past studies, on a 5 point Likert scale ranging from highly disagree to highly agree. Exploratory factor analysis summarized all the measurement items into seven main factors from which two factors were removed due to lcademicians, marketers and decision-makers to understand different facets of consumer behaviour in three contagious countries namely Bangladesh, India and Pakistan in South Asia.Therefore, more COVID-19 crisis perception leads to significant changes in consumption pattern and the financial situation of the consumers. This study will enable academicians, marketers and decision-makers to understand different facets of consumer behaviour in three contagious countries namely Bangladesh, India and Pakistan in South Asia.The Covid-19 pandemic has disrupted the education sector, including kindergartens. Kindergarten principals and teachers make extra effort to maintain their education performance. This research aims to identify problems of the "learning from home" policy in kindergarten education and formulate possible solutions to overcome them. It involved 15 respondents from different regions in Indonesia. Data were collected through several methods, including face-to-face interviews, phone interviews, and online interviews through messaging services. The research result showed that many kindergarten management boards encountered difficulties in fulfilling planned education schedules and had the low achievement of objective targets. The problems existed in teachers, parents, and mainly students. Most teachers faced problems in creating interactive education materials and conducting an evaluation. Parents had hard times in assisting their children due to their busy activities and low pedagogical competence. Children had hard times due to limited resources for online learning. JG98 This research suggests solutions such as improving the mastery of information and communication technology (ICT), especially for teachers, parents, and children. However, the education system's long-term reform is needed to prepare for facing the possible catastrophe that affects the education system. It may include integrating online learning in the traditional education system and the development of supporting infrastructure and facilities.TPPP proteins exhibiting microtubule stabilizing function constitute a eukaryotic protein superfamily, characterized by the presence of the p25alpha domain of various lengths. Vertebrate species possess three TPPP paralogs; all of them possess a full-length p25alpha domain of 160-170 amino acids and are encoded by three exons. Species of Endopterygota (Holometabola) have, besides a full-size TPPP ortholog, a protein with a truncated p25alpha domain as well, where the last coding exon, responsible for microtubule binding, is missing. It is not the result of an alternative splicing but is coded by another gene. In Drosophila melanogaster, they are named as CG45057 (long-type) and CG6709 (truncated). The truncated protein has been found in the Endopterygota orders Diptera, Coleoptera, Hymenoptera, Lepidoptera and Raphidioptera. In Lepidoptera, in several superfamilies (Gelechioidea, Bombycoidea, Noctuoidea, Pyraloidea) two paralogs of the truncated TPPP occur. Truncated orthologs (CG6709) were not found in other insects or in arthropods and are absent in any other organism, as well, while the long-type TPPPs (CG45057 orthologs) occur commonly in all animals.