This cross-sectional study aimed to assess the factors in dentists' opinions related to oral health and the treatment management of the elderly. An online questionnaire-based survey was conducted among the dentist population (n = 463). Respondents were divided depending on whether they attended the geriatric dentistry course during their education, and 15 questions on the Likert scale demonstrated the difference in their attitudes. The majority of respondents (61.9%) agree that dental studies should pay more attention to acquiring sufficient knowledge and skills in the treatment of the elderly, and 56.2% would like to attend a course on that subject. Compared to those who participated in the geriatric dentistry course, those who did not consider providing oral healthcare to older people find it more difficult because of its complexity and practical obstacles (37.3% vs. 54%, p ≤ 0.001). From the results of this study, it can be concluded that there are differences in opinion about the provision of oral healthcare to the elderly between dentists who have and who have not attended a geriatric dentist course during their education. During the dentist's education, geriatric dentistry courses should have a significant role in providing knowledge for working with the elderly population.Background and Objectives Cardiac involvement in systemic sclerosis has important consequences on patient survival. Myocardial fibrosis and microcirculation involvement can generate arrhythmic complications, which can be associated with a higher death risk. QT interval prolongation is considered as a risk factor for ectopic ventricular events and can be evaluated using standard short ECG recordings or 24-h Holter ECG recordings. Materials and Methods 39 patients with systemic sclerosis were submitted to a standard ECG recording at admission and 24-h Holter ECG monitoring. Results QT interval values resulted from Holter ECG monitoring are higher than the values generated by the short-term ECG recordings. Holter ECG monitoring permits the detection of ventricular ectopy in patients with no events on standard ECG. Conclusions In patients with systemic sclerosis, 24-h Holter ECG recordings can realize a more precise evaluation of the extent of QTc interval prolongation and ventricular ectopic events associated with myocardial involvement.Sensor networks have become more popular in recent years, now featuring plenty of options and capabilities. Notwithstanding this, remote locations present many difficulties for their study and monitoring. High-frequency (HF) communications are presented as an alternative to satellite communications, being a low-cost and easy-to-deploy solution. Near vertical incidence skywave (NVIS) technology provides a coverage of approximately 250 km (depending on the frequency being used and the ionospheric conditions) without a line of sight using the ionosphere as a communication channel. This paper centers on the study of the ionosphere and its characteristic waves as two independent channels in order to improve any NVIS link, increasing its robustness or decreasing the size of the node antennas through the appliance of specific techniques. We studied the channel sounding of both the ordinary and extraordinary waves and their respective channels, analyzing parameters such as the delay spread and the channel's availability for each wave. The frequency instability of the hardware used was also measured. find more Furthermore, the correlation coefficient of the impulse response between both signals was studied. Finally, we applied polarization diversity and two different combining techniques. These measurements were performed on a single frequency link, tuned to 5.4 MHz. An improvement on the mean bit energy-to-noise power spectral density (Eb/N0) was received and the bit error rate (BER) was achieved. The results obtained showed that the extraordinary mode had a higher availability throughout the day (15% more availability), but a delayed spread (approximately 0.3 ms mean value), similar to those of the ordinary wave. Furthermore, an improvement of up to 4 dB was achieved with the usage of polarization diversity, thus reducing transmission errors.Structural health monitoring (SHM) is crucial for quantitative behavioral analysis of structural members such as fatigue, buckling, and crack propagation identification. However, formerly developed approaches cannot be implemented effectively for long-term infrastructure monitoring, owing to power inefficiency and data management challenges. This study presents the development of a high-fidelity and ultra-low-power strain sensing and visualization module (SSVM), along with an effective data management technique. Deployment of 24-bit resolution analog to a digital converter and precise half-bridge circuit for strain sensing are two significant factors for efficient strain measurement and power management circuit incorporating a low-power microcontroller unit (MCU), and electronic-paper display (EPD) enabled long-term operation. A prototype for SSVM was developed that performs strain sensing and encodes the strain response in a QR code for visualization on the EPD. For efficient power management, SSVM only activated when the trigger-signal was generated and stayed in power-saving mode consuming 18 mA and 337.9 μA, respectively. The trigger-signal was designed to be generated either periodically by a timer or intentionally by a push-button. A smartphone application and cloud database were developed for efficient data acquisition and management. A lab-scale experiment was carried out to validate the proposed system with a reference strain sensing system. A cantilever beam was deflected by increasing load at its free end, and the resultant strain response of SSVM was compared with the reference. The proposed system was successfully validated to use for long-term static strain measurement.Phosphodiesterase 7 (PDE7) is an enzyme responsible for the degradation of cyclic adenosine monophosphate (cAMP), an important cellular messenger. PDE7's role in neurotransmission, expression profile in the brain and the druggability of other phosphodiesterases have motivated the search for potent inhibitors to treat neurodegenerative and inflammatory diseases. Different heterocyclic compounds have been described over the years; among them, phenyl-2-thioxo-(1H)-quinazolin-4-one, called S14, has shown very promising results in different in vitro and in vivo studies. Recently, polymeric nanoparticles have been used as new formulations to target specific organs and produce controlled release of certain drugs. In this work, we describe poly(lactic-co-glycolic acid) (PLGA)-based polymeric nanoparticles loaded with S14. Their preparation, optimization, characterization and in vivo drug release profile are here presented as an effort to improve pharmacokinetic properties of this interesting PDE7 inhibitor.