The aim of this study was to evaluate the indications, adverse reactions, and outcome of therapeutic plasma exchange (TPE) in myasthenia gravis (MG) patients. Retrospective Observational study. A total of 18 patients of MG had undergone 18 cycles and 87 session of TPE at our Institution, a tertiary care center in Western India. It was performed using a single volume plasma exchange with intermittent cell separator (Freseniouscomtec), subclavian central line access, and with alternate day interval. Outcome was assessed shortly after each session and overall outcome at the time of discharge. Total of 68 patients of MG were admitted to Neurology Intensive care unit (ICU) during the study period [January 2016-December 2019]. Out of them, TPE was done in 18 patients. Among the 18 patients, 11 patients had myasthenic crisis and 7 patients had worsening of MG. The mean number of TPE session was 4.2(SD ± 1.2), volume exchange was 2215 ml (SD ± 435); overall incidence of adverse reaction was 33.3%. All patients had immediate benefits of each TPE cycle. Good acceptance of procedure was observed in 72.2% of patients. TPE is cost-effective rapid therapy for myasthenic crisis and progressive myasthenia gravis. It reduces ICU stays and improves outcome.TPE is cost-effective rapid therapy for myasthenic crisis and progressive myasthenia gravis. It reduces ICU stays and improves outcome. Occupational safety and health hazards in healthcare facilities play a significant role in the lives of care providers and also contribute toward quality patient care. Healthcare workforce gets exposed to physical, chemical, biological, and psychological hazards while discharging their duties, thus demanding for proper knowledge and awareness to address the same. As nursing staff implement the care process directed by the physicians, the current study conducted at a teaching hospital aimed at assessing their awareness on occupational safety and health hazards. A prospective study was conducted on a pilot basis for a period of 3 months in various nursing areas of the hospital. The questionnaire aimed at assessing the awareness of nursing staff on occupational safety and health hazards (5-point scale) was administered on nursing staff (150/170]. Total scores and percentage of responses were computed and the degree of correlation was observed as 0.4 between the participants age, educational qualifications,had highlighted the areas that require knowledge enhancement on occupational safety and health hazards which helps in adopting the best practices at workplace.The study had highlighted the areas that require knowledge enhancement on occupational safety and health hazards which helps in adopting the best practices at workplace. Diabetic foot is the most common complication among 50% diabetic patients. Evidence exists that with the self-care, the incidence of foot ulcers and toe amputation can be decreased significantly. Hence, the current study was planned to assess knowledge and foot care practice among diabetic patients attending primary care centre in Saudi Arabia. This prospective cross-sectional study was conducted at a Primary Care Center in Security Forces Hospital of Riyadh. Consecutive sampling was used to enrol 350 diabetic patients. Information on demographics, knowledge and practice of footcare was collected through standardized and pre-tested self-administered questionnaire. Data were entered and analysed using SPSS V 22.0 software. Out of 350 patients aged 18 years and more, 170 (46.7%) belonged to age group of 46-60 years; mostly males ( = 185, 53.9%). The foot complications were absent among 57.9% patients, 35.5% having numbness, 4.3% having a history of healed ulcer and 2.3% reported toe amputation. More than 65% patients were certain about their knowledge regarding foot self-care. There was no statistically significant difference in the knowledge among males and females. The practice of self-care of feet was statistically significantly different among males and females regarding self-inspection of feet on regular basis as well as daily moisturizing of their feet. Both knowledge and practice levels were low among diabetic patients which needs to be strengthened through regular counselling sessions. There is a pressing need to spread awareness on this important aspect of morbidity and mortality which can be addressed with minimal resources.Both knowledge and practice levels were low among diabetic patients which needs to be strengthened through regular counselling sessions. read more There is a pressing need to spread awareness on this important aspect of morbidity and mortality which can be addressed with minimal resources. Acute Encephalitis Syndrome (AES) in children contributes considerable morbidity and mortality in endemic region. A study was conducted to see the clinico-epidemiological characteristics of hospitalized AES children and to find out if there is any correlation of clinico-epidemiological factors with case fatality rate (CFR). This hospital-based observational prospective study was conducted in a tertiary care teaching hospital of Assam, India from 16 May, 2019 to 15 May, 2020. We enrolled clinically diagnosed 140 hospitalized AES children consecutively as per WHO case definition. Cerebrospinal fluid and serum samples were tested for JEV-specific IgM antibodies. Out of 140 AES children 84 (60%) were male and 5-12 years age group had the highest 79 (56.4%) number of cases. Primarily cases were from rural areas 132 (94.3%). In addition to fever, major clinical manifestations were seizures 114 (81.4%), altered sensorium 128 (91.4%), meningeal signs 62 (44.3%), and <8 GCS 42 (30%). CFR was 27.7%. Significantly high CFR was seen among AES children with GCS <8 (P-value 0.0001) and presence of meningeal signs (P-value 0.0007). A higher proportion of non-survivors 55.6% were non JE AES. Monthly incidence of AES/Death showed a peak in the month of July. AES in children is a significant public health problem in the study area with high CFR. Presence of GCS <8 and meningeal irritation are the important predictors of mortality in AES children. Preponderance of non-JE AES case fatality in children warrant further exploration and appropriate public health interventions.AES in children is a significant public health problem in the study area with high CFR. Presence of GCS less then 8 and meningeal irritation are the important predictors of mortality in AES children. Preponderance of non-JE AES case fatality in children warrant further exploration and appropriate public health interventions.