BACKGROUND & AIMS In 2018, the Global Leadership Initiative on Malnutrition (GLIM) presented the criteria for malnutrition diagnosis; reports about the proportion of malnutrition patients meeting these GLIM criteria in acute care hospitals, however, remain very limited. The relationship between GLIM criteria and existing nutritional indicators, patterns for hospitalization, and malnutrition severity is also unclear. This study aims to investigate this relationship. METHODS Our study included 490 patients (aged 69.5 ± 16.0 years, 45% women) who had been hospitalized during a specific month in an acute care hospital, and for whom we could assess nutritional status according to GLIM criteria. We analyzed the cut-off value on the MNA-SF score and grip strength (GS) for GLIM criteria-defined malnutrition severity grading with receiver operating characteristic (ROC) analysis. We extracted factors relating to malnutrition by multivariate logistic regression analysis. RESULTS In all, 33% of patients met the GLIM critthen  0.001). CONCLUSIONS Using the MNA-SF for GLIM criteria screening, we identified malnourished patients with high accuracy, and GS was also a reliable nutritional assessment. Emergency hospitalization patients were at a high risk for malnutrition. Agroecology has been suggested as a promising concept for reconciling agricultural production and environmental sustainability by optimizing ecological processes that deliver ecosystem services (ES) to replace external inputs. While this statement is widely agreed upon, few assessments of real-life conditions exist that assess multiple ES simultaneously. This paper provides an assessment of seven ES based on 14 indicators in three agroecological farming systems (AFS) and thirteen of their adjacent conventional farming systems (CFS). Based on field-scale measurements spread over three years, our findings suggest that the studied AFS succeed in providing a wider array of regulating services than their neighboring CFS. Soil aggregate stability and soil respiration rates are in general more supported in AFS, which also show lower pest abundance. On the other hand, CFS show higher grain production and higher performance for two out of three fodder quality indices. While this 'productivity gap' may be due to the still-evolving state of the studied AFS, we nuance this through the lens of an emerging paradigm to assess farming system multi-performance. It is now argued that we need to shift from a volume-focused production system to a system that also values the ecological processes underpinning crop production and other benefits to society. Based on our findings, we recommend future work to iterate our initiative, including several indicators per service and embed these into a wider context of co-adaptive science-practice to further develop context-specific and user-useful research. Patients who carry the BReast Cancer 1 or 2 (BRCA) gene mutations have an underlying hereditary predisposition for breast and ovarian cancers. These deleterious genetic mutations are the most common ones implicated in hereditary breast and ovarian cancers. Oncogenetic counselling plays a key role in identifying patient for BRCA testing and for mutation identification. BRCA1/2 carriers have to be followed up regularly and may justify breast and/or adnexal prophylactic surgery, according to the French National Cancer Institute guidelines (INCa). Poly- (DNA-riboses) polymerases inhibitors, notably olaparib, have a major role in the management of epithelial ovarian cancer in patients with BRCA mutation and many studies are ongoing to expand their indications in a near future. SKI II concentration It is paramount to identify patients whose cancer is associated with genetic susceptibility to the disease, since their long-term management depends on it. Anatomical and molecular pathologists play a key role in the process. Indeed, their diagnosis supports or even sometimes warrants germline genetic testing. For example, a colorectal cancer with mismatch repair protein expression loss suggests Lynch syndrome, while a rare type of renal cell carcinoma with fumarate hydrate expression loss is highly evocative of hereditary leiomyomatosis and renal cell carcinoma syndrome. Similarly, the presence of the T790M EGFR variant before treatment in a non-small-cell lung carcinoma warrants further testing as the variant is likely of germline origin. Patients with suspected genetic susceptibility to cancer are referred to the nearest clinical cancer genetics clinic. The cancer geneticist, assisted by a genetic counsellor, then collects detailed personal and familial information, sometimes feeds them into bioinformaticsr the oncologists, the development of mainstreaming programs where they are allowed to prescribe germline testing under the supervision of a cancer genetics team is unavoidable. Methane leaking at depth from hydrocarbon wells poses an environmental and safety hazard. However, determining the occurrence and magnitude of gas migration at ground surface is challenging, as part of the leaking gas is retained during upward migration. We investigated migration through unconsolidated sedimentary aquifers using a two-phase, two-component (water and methane) flow and transport model constructed in DuMux. A sensitivity analysis for migration through a 60 m thick sandy aquifer showed that retention by dissolution can be significant even with low groundwater Darcy velocities of 1 m.yr-1. Retention was negligible in the absence of groundwater flow. Besides groundwater velocity, both hydrogeological (permeability, entry pressure, pore-size distribution, and residual gas saturation) and leakage conditions (depth, magnitude and spatial dimensions) determined model outcomes. Additional simulations with interbedded finer grained sediments resulted in substantial lateral spreading of migrating gas. This delayed upward migration and enhanced retention in overlying sandy units where groundwater velocities are highest. Overall, the results of this study show that for unconsolidated aquifer systems and the most commonly observed leakage rates (0.1-10 m3.d-1), significant amounts of migrating methane can be retained due to dissolution into laterally flowing groundwater. Consequently, resulting atmospheric methane emissions above such leaks may be delayed with decades after the onset of leakage, significantly reduced, or prevented entirely.