05 μM (s/n = 3). The fabricated platform was successfully used for on-site analysis of phosphate in turbid coastal waters. This reliable and effective method for the analysis of phosphate in turbid coastal waters allows for sensitivity and anti-interference determination, while also representing a significant step towards comprehensive and convenient analysis of phosphorus species. We aimed to assess the incidence of dementia over time in patients with incident rheumatoid arthritis (RA) as compared to non-RA referents. This population-based, retrospective cohort study included Olmsted County, Minnesota residents with incident RA by ACR 1987 criteria, diagnosed between 1980 and 2009. We matched non-RA referents 11 on age, sex, and calendar year and followed all individuals until 12/31/2019. Incident dementia was defined as two codes for Alzheimer's disease and related dementias (ADRD) at least 30 days apart. Cumulative incidence of ADRD was assessed, adjusting for the competing risk of death. Cox proportional hazards models calculated hazard ratios (HR) with 95% confidence intervals (CI) for incident ADRD by decade. After excluding individuals with prior dementia, we included 897 persons with incident RA (mean age 56 years; 69% female) and 885 referents. The 10-year cumulative incidence of ADRD in individuals diagnosed with RA during the 1980s was 12.7% (95%CI7.9-15.7%), 1990s was 7.2% (95%CI3.7-9.4%), and 2000s was 6.2% (95%CI3.6-7.8%). Individuals with RA diagnosed in 2000s had insignificantly lower cumulative incidence of ADRD than those in the 1980s (HR 0.66; 95%CI0.38-1.16). The overall HR of ADRD in individuals with RA was 1.37 (vs. referents; 95%CI1.04-1.81). When subdivided by decade, however, the risk of ADRD in individuals diagnosed with RA was higher than referents in the 1990s (HR 1.72, 95%CI1.09-2.70) but not 2000s (HR 0.86, 95%CI0.51-1.45). The risk of dementia in individuals with RA appears to be declining over time, including when compared to general population referents.The risk of dementia in individuals with RA appears to be declining over time, including when compared to general population referents.A novel electrochemical Advanced Oxidation System (AOS) has been recently developed for water disinfection where iodide is used to generate active iodine species in-situ. However, the presence of iodide during water disinfection can lead to the formation of iodinated disinfection byproducts (I-DBPs), which have been shown to be more cyto- and genotoxic than their chlorinated and brominated analogs. In this study, the formation of DBPs was assessed in ultrapure water, river water and secondary wastewater effluents treated by the AOS. A comprehensive total organic halogen and target DBP analysis was used that included 25 unregulated DBPs, and the total organic halogen (TOX) quantified as total organic chlorine (TOCl), total organic bromine (TOBr), and total organic iodine (TOI). Ultrapure water disinfection only quantified iodoform (TIM) at a maximum concentration of 0.90 ± 0.05 µg/L. River water results show that TOI increase from 1.3 ± 0.3 µg/L before disinfection (t = 0) to a maximum of 3.5 ± 1.1 µg/L. TIM and bromodiiodomethane (BDIM) were the only targeted iodo-trihalomethanes (I-THMs) that were quantified with a maximum total I-THM concentration of 0.44 µg/L. Secondary wastewater effluent disinfection results show that TOI increased from 1.8 ± 0.3 µg/L (t = 0) to a maximum concentration of 35.3 ± 0.3 µg/L. Iodide and iodate were the main iodinated species exiting the AOS system with a iodine recovery of 94-101%. The results from this study show that the AOS formed low levels of iodinated DBPs in treated water sources that are comparable to the levels found in disinfected drinking water and wastewater.With the rapid growth of the economy, there are increasing conflicts between economic development and environmental protection. Among these conflicts, the wastewater emission management as one of the significant ways to alleviate water scarcity has been paid increasing attention across the developing countries, such as China. It is thus essential to comprehensively investigate the enviro-economic effects induced by wastewater-related policies. In this study, a factorial emission-focused general equilibrium model (FEGE) is first developed to facilitate examine the composite enviro-economic effects of multiple policy scenarios with regards to wastewater-related environmental taxes and the related subsides. A special case study for the Municipality of Chongqing, China, is conducted to illustrate the potential benefits of its use in the formulation of wastewater-related policies. It is found that the impacts of various wastewater-related policies (i.e., environmental taxes and the related subside) on GDP are different. selleck In detail, green tax policies on GDP are negative, while wastewater emission intensity (WEI) improvement policies on GDP are positive. When green tax reaches 14 yuan/tonne, which is the maximum proposed by the Chinese government, the GDP will drop by 0.37%, which would be deemed acceptable for the Municipality of Chongqing. In addition, the impacts on rural households' consumption are greater than those on urban households' consumption whichever the application of wastewater-related policies; it is because the rural households in the Municipality of Chongqing have a relatively unitary income source. It is thus recommended that the rural household in Chongqing should be paid more attention. For example, some extra allowances could be considered to the rural household to help them cope with the negative economic impacts induced by a new environmental policy. It is expected that the outputs would provide bases for formulating desired wastewater-related policies.Finding a low cost and effective alternative to noble metal based catalyst has long been concerned in wastewater treatment and organic transformation. This work developed a highly efficient sewage sludge-based catalyst via a simple one-step pyrolysis method, and for the first time, applied it in the catalytic reduction of nitrophenols. Due to the higher content of graphitic nitrogen, abundant defect sites and low electron transfer resistance, sewage sludge derived biochar obtained at 800 °C (SSBC-800) exhibits the best catalytic performance, with the reaction rate of 0.48 min-1 and turnover frequency for 4-nitrophenol calculated to be 1.25 × 10-4 mmol•mg-1 min-1, which is comparable to or even superior than some reported noble metal-based catalyst. Moreover, SSBC-800 showed good recyclability of 90% 4-nitrophenol removal within 8 min after 4 runs, and maintained high catalytic activity in reduction of other substituent nitrophenols, such as 2-nitrophenol (0.54 min-1), 3-nitrophenol (0.61 min-1) and 2,4-dinitrophenol (0.