2 mg/L in TCLP tests. RM acts as a highly effective arsenic remover and stabilizer for the disposal of high-arsenic wastewater. It shows great potential for the remediation of wastewater containing heavy metals with varying concentrations to produce clean water available for industrial purpose.Acrylamide (ACR) is a widely used environmentally hazardous compound that is known to be neurotoxic, genotoxic, carcinogenic, and reproductive toxicity. It is widely present in soil, water, agents used in chemical industries, and food. It can be distributed to all organs and tissues, and can cause damage to various human systems and those of other animals. Previous metabolomics studies have mainly focused on metabolites in serum and urine, but have lacked comprehensive analysis of major organs and tissues. In the current study, a gas chromatography-massspectrometry method was used to investigate mechanisms underlying organ toxicity, in an effort to identify potentially sensitive biomarkers in the main target tissues of rats after ACR exposure. Male Sprague-Dawley rats were assigned to two groups; a control group and a group treated with 20 mg kg-1 ACR intragastrically for 6 weeks. Metabolite changes in the two groups were statistically analyzed. The respective numbers of altered metabolites in the hippocampus, cortex, kidney, serum, heart, liver, and kidney fat were 21, 21, 17, 5, 15, 14, and 6. There were 14 metabolic pathways related to amino acid, fatty acid, purine, and energy metabolism, revealing that the toxic mechanism of ACR may involve oxidative stress, inflammation, and amino acid metabolism and energy disorders.Previous nationwide studies have reported links between long-term concentrations of fine particulate matter (PM2.5) and COVID-19 infection and mortality rates. In order to translate these results to the state level, we use Bayesian hierarchical models to explore potential links between long-term PM2.5 concentrations and census tract-level rates of COVID-19 outcomes (infections, hospitalizations, and deaths) in Colorado. We explicitly consider how the uncertainty in PM2.5 estimates affects our results by comparing four different PM2.5 surfaces from academic and governmental organizations. After controlling for 20 census tract-level covariates, we find that our results depend heavily on the choice of PM2.5 surface. Orludodstat nmr Using PM2.5 estimates from the United States EPA, we find that a 1 μg/m3 increase in long-term PM2.5 concentrations is associated with a statistically significant 26% increase in the relative risk of hospitalizations and a 34% increase in mortality. Results for all other surfaces and outcomes were not statistically significant. At the same time, we find a clear association between communities of color and COVID-19 outcomes at the Colorado census tract level that is minimally affected by the choice of PM2.5 surface. A per-interquartile range (IQR) increase in the percent of non-African American people of color was associated with a 31%, 43%, and 56% increase in the relative risk of infection, hospitalization, and mortality respectively, while a per-IQR increase in the proportion of non-Hispanic African Americans was associated with a 4% and 7% increase in the relative risk of infections and hospitalizations. The current disagreement among the different PM2.5 estimates is a key factor limiting our ability to link environmental exposures and health outcomes at the census tract level. These results have strong implications for the implementation of an equitable public health response during the crisis and suggest targeted areas for additional air monitoring in Colorado.Endocrine-disrupting chemicals (EDCs) in water are receiving particular attention as they pose adverse effects on aquatic systems, even at trace concentrations. A comprehensive study was conducted on 14 EDCs (five estrogens and nine household and personal care products (HPCPs)) in the water of the urbanized Jiaozhou Bay in the Yellow Sea during summer and winter. Results showed that the total concentration of 14 EDCs ranged from 100 to 658 ng L-1 and 56.7-212 ng L-1 in the estuarine and bay water, respectively. The average total concentration of five estrogens in summer was significantly (p 1).Sulfate (SO4•-) and hydroxyl-based (HO•) radical are considered potential agents for As(III) removal from aquatic environments. We have reported the synergistic role of SO4•- and HO• radicals for As(III) removal via facile synthesis of biochar-supported SO4•- species. MoS2-modified biochar (MoS2/BC), iron oxide-biochar (FeOx@BC), and MoS2-modified iron oxide-biochar (MoS2/FeOx@BC) were prepared and systematically characterized to understand the underlying mechanism for arsenic removal. The MoS2/FeOx@BC displayed much higher As(III) adsorption (27 mg/g) compared to MoS2/BC (7 mg/g) and FeOx@BC (12 mg/g). Effects of kinetics, As(III) concentration, temperature, and pH were also investigated. The adsorption of As(III) by MoS2/FeOx@BC followed the Freundlich adsorption isotherm and pseudo-second-order, indicating multilayer adsorption and chemisorption, respectively. The FTIR and XPS analysis confirmed the presence of Fe-O bonds and SO4 groups in the MoS2/FeOx@BC. Electron paramagnetic resonance (EPR) and radical quenching experiments have shown the generation of SO4•- radicals as predominant species in the presence of MoS2 and FeOx in MoS2/FeOx@BC via radical transfer from HO• to SO42-. The HO• and SO4•- radicals synergistically contributed to enhanced As(III) removal. It is envisaged that As(III) initially adsorbed through electrostatic interactions and partially undergoes oxidation, which is finally adsorbed to MoS2/FeOx@BC after being oxidized to As(V). The MoS2/FeOx@BC system could be considered a novel material for effective removal of As(III) from aqueous environments owing to its cost-effective synthesis and easy scalability for actual applications.To preserve the Europe consumers' health, the use of glucocorticoids as growth promoters is prohibited in cattle fattening. In 2008, the Italian Ministry of Health associated to the official control a national monitoring plan based on the histological thymus analysis to identify animals illegally treated with corticosteroids. However, since corticosteroids are authorized and widely used for therapeutic purposes, it is necessary to verify whether the thymus histological test and some physicochemical traits in meat are able to discriminate doped calves from dexamethasone therapeutic treated ones. The aims of this study were (i) to establish whether the therapeutic and illicit corticosteroid treatments of calves could be differentiated through histological evaluation of thymus and by physicochemical meat traits; (ii) to identify a restricted number of physicochemical traits that could differentiate dexamethasone treated from untreated calves. Three groups of 15 calves each were included in this study group dexamethasone therapeutic treatment treated with dexamethasone 21-phosphate disodium salt at a therapeutic dose (2 mg/kg of live weight for three consecutive days); group dexamethasone anabolic treatment orally treated with dexamethasone 21-phosphate disodium salt according to a presumed anabolic protocol (0.