Our study incriminated new vectors of knowlesi malaria in Sarawak and underscores the importance of including entomological studies during the daytime to obtain a comprehensive understanding of the transmission dynamics of malaria.Novel biosorbents were derived from a waste product of palm kernel oil extraction known as palm kernel chaff (PKC). One portion of the PKC was carbonized in a furnace and then activated chemically, while the other half was activated without carbonization. Both were designated as CPKC and UPKC, respectively. The two biosorbents so produced were then used to conduct batch equilibrium and kinetic sorption studies at 30 °C, 35 °C and 40 °C and pH 3.0 and 9.0 for an agitation period of 5, 10, 20, 40, 60, 90, and 120 min. The Koble-Corrigan, Dubinin-Radushkevich, and the Freundlich isotherms fitted the experimental data very well with R2 values of 0.97 to 1.0, 0.95 to 1.0, and 0.96 to 1.0, respectively. The linear type II Langmuir isotherm performed much better (0.96 ≤ R2 ≤ 1.0) than the nonlinear isotherm. The maximum sorption capacity was obtained as 120.6 mg/g using CPKC at pH 9.0 and 35 °C. The Langmuir separation coefficient values (0.022 ≤ RL ≤ 0.926) show that the sorption of nickel to PKC is favorable. The most favorable sorption condition was found for CPKC at pH 9 and temperature of 40 °C. The values of sorption energy (8.21 ≤ E ≤ 14.27) and the isosteric heat of sorption (-133.09 ≤ ∆Hx ≤ -17.92) indicate that the mode of sorption is mostly ion exchange. Thermodynamic parameters also show that the process is exothermic and entropy-driven. The pseudo-second-order kinetic model shows the best correlation compared to the other kinetic models. The coefficient of correlation for the pseudo-second-order model was mostly within the range of 0.999-1.000 for 90% of all kinetic studies carried out.A severe consequence of radiation therapy in patients with head and neck cancer is persistent salivary gland hypofunction which causes xerostomia and oral infections. We previously showed that irradiation (IR) of salivary glands in mice triggers initial transient increases in mitochondrial reactive oxygen species (ROSmt), mitochondrial [Ca2+] ([Ca2+]mt), and activated caspase-3 in acinar cells. In contrast, loss of salivary secretion is persistent. Herein we assessed the role of ROSmt in radiation-induced irreversible loss of salivary gland function. We report that treatment of mice with the mitochondrial-targeted antioxidant, MitoTEMPO, resulted in almost complete protection of salivary gland secretion following either single (15 Gy) or fractionated (5 × 3 Gy) doses of irradiation. Salivary gland cells isolated from MitoTEMPO-treated, irradiated, mice displayed significant attenuation of the initial increases in ROSmt, ([Ca2+]mt, and activated caspase-3 as compared to cells from irradiated, but untreated, animals. Importantly, MitoTEMPO treatment prevented radiation-induced decrease in STIM1, consequently protecting store-operated Ca2+ entry which is critical for saliva secretion. Together, these findings identify the initial increase in ROSmt, that is induced by irradiation, as a critical driver of persistent salivary gland hypofunction. We suggest that the mitochondrially targeted antioxidant, MitoTEMPO, can be potentially important in preventing IR-induced salivary gland dysfunction.The continuously increased existence of contaminants such as chemical and biological mainly dye, bacteria, and heavy metals ions (HMI) in water bodies has increased environmental concern due to their hostile effects on living things. Therefore, there is necessity to be developed newer materials that skirmishes such environmental menace. The present works focus on the synthesis of a novel three-dimensional (3D) polymer-metal-carbon (3D-PMC) framework for the exclusion of contaminants (chemical and biological) from water bodies. Initially, polyurethane (PU) foam was treated with nitric acid and used as a framework for the development of 3D-PMC materials. The copper nanosheet (Cu-NS) was deposited onto the functionalized PU foam to produce Cu-NS-PU material. The mechanically exfoliated graphene was mixed with chitosan to produce a graphene-chitosan homogenous suspension. The produce homogenous suspension was deposited Cu-NS-PU for the development of the 3D-PMC framework. The prepared 3D-PMC framework was characterized by scanning electron microscopy (SEM), Energy Dispersive X-Ray Analysis (EDX), Fourier-transform infrared spectroscopy (FT-IR), and X-rays diffraction (XRD) analysis. The prepared 3D-PMC framework was subjected to various adsorption parameters to assess the sorption ability of the material. The prepared 3D-PMC framework was effectively used for the removal of chromium (Cr) metal ions and Congo-red (CR) dye from the water system. The synthesis of the 3D-PMC framework is simple, novel, cost-effective, and economically viable. Therefore, the prepared 3D-PMC framework has the potential to be used as a filter assembly in water treatment technologies.Nutritional symbioses between bacteria and insects are prevalent and diverse, allowing insects to expand their feeding strategies and niches. A common consequence of long-term associations is a considerable reduction in symbiont genome size likely influenced by the radical shift in selective pressures as a result of the less variable environment within the host. While several of these cases can be found across distinct insect species, most examples provide a limited view of a single or few stages of the process of genome reduction. Stink bugs (Pentatomidae) contain inherited gamma-proteobacterial symbionts in a modified organ in their midgut and are an example of a long-term nutritional symbiosis, but multiple cases of new symbiont acquisition throughout the history of the family have been described. We sequenced the genomes of 11 symbionts of stink bugs with sizes that ranged from equal to those of their free-living relatives to less than 20%. Comparative genomics of these and previously sequenced symbionts revealed initial stages of genome reduction including an initial pseudogenization before genome reduction, followed by multiple stages of progressive degeneration of existing metabolic pathways likely to impact host interactions such as cell wall component biosynthesis. Amino acid biosynthesis pathways were retained in a similar manner as in other nutritional symbionts. Suzetrigine datasheet Stink bug symbionts display convergent genome reduction events showing progressive changes from a free-living bacterium to a host-dependent symbiont. This system can therefore be used to study convergent genome evolution of symbiosis at a scale not previously available.