ently described in a large single-centre series with an overall incidence of 7%. Disease recurrence was also observed in recipients with pretransplant hypercoagulability and morbid obesity with respective incidences of 4 and 24%. selleck compound As expected, tumour recurrence is largely determined by type, extent and biologic behaviour of the primary neoplasm. With the exception of high-grade aggressive malignancy, disease recurrence is still of academic interest with no significant impact on overall short and long-term outcome. The most demanding scenarios and physical demands of elite basketball 5-on-5 scrimmages are unknown to trainers, although recent advances in microtechnology allows the gaps in this research to be filled. The purpose of this study was to describe and compare the physical demands, through the most demanding scenarios and traditional average measures, of two different 5-on-5 scrimmage situations executed during training sessions in elite male basketball players. Physical demand measures (i.e., total distance covered, high-speed running distance, number of high-intensity accelerations actions, number of high-intensity decelerations actions) were collected from 12 players from the Spanish first Division using a Local Positioning System. Measures were compared via a Bayesian inference analysis, considering playing in half-court (HALF) and half-court and transition (HTRAN) conditions for the 5-on-5 scrimmage. This study showed that, irrespective of the approach used to quantify the physical demands (traditionase periods of activity. Based on the physical demands described, HTRAN may be used to help train players to perform optimally during the most physically-stressful scenarios of match-play whereas HALF may be more suitable to be included in warm- ups, recovery sessions and sessions immediately before a match. This study investigated the effects of warm temperature in the external environment on 1) physiological response in self- pace during the long-distance race in runners; and 2) the association between the physiological index of endurance performance (i.e., speeds at ventilatory anaerobic threshold (VVAT), respiratory compensation (VRCP), maximum oxygen uptake (VVO2max), and running economy) and average pace for each 3- km during the 21- Km race. Five male recreational runners (mean + SE age 36.6 + 6.1 years; VO2 max 59.2 + 7.9) were submitted to a 21-kilometers race in the outdoor environment using a portable metabolic analyzer. Our results showed a reduction in speed to kilometers 12,15,18 and 21 than kilometer 3 (P<0.05). Likewise, the runners showed a decrease in both VO2 (ml/kg/min) and RER from kilometer 15 (P=0.001 and P=0.003, respectively). Regarding cardiovascular response, our data demonstrated a steady HR response from kilometer 6 to 21 (P=0.99). Otherwise, the runners showed a decrease in cardiovascular and metabolic strain in runners. Concerning physiological markers of endurance performance, VVAT appears to be the best predictor of the average pace throughout the 21-Km race in a warm environment in recreational runners.Focus on Youth Football and Alcohol (FYFA) is a European project (EC, 3rd Health Program, HP-PJ-2016) involving research institutions from Belgium, Finland, Italy, Poland, Slovenia and the UK. The Istituto Superiore di Sanità (ISS), was the project leader of Work Package 5 "Review of national policies and practice in six Member States related to alcohol, young people, sport, marketing and football." The aim of WP5 was to determine the status quo of the policies and practices to reduce heavy episodic drinking related to young people, alcohol and sport at national level. This work investigates knowledge, attitudes and perceptions of experts from sport settings and from the prevention area giving insights on the perceived obstacles and facilitators, whenever available, to promote strategies to reduce alcohol related harm in youth within sport contexts. The presented work describes laws, regulations and attitudes. Furthermore, the results help identifying areas requiring development, highlighting examples of good practices. It emerges that prevention of alcohol-related harm to youth is important within sport settings and should be a priority for all FYFA countries. Despite the presence of regulations, there is a low level of knowledge and enforcement at national level and in the sport contexts; and there is the need of cooperation across organizations to implement alcohol policies for youth within sport settings. More efforts and resources are needed to overcome the main obstacles for effective implementation of alcohol policies, such as regulations on advertising and sponsorship, and alcohol selling, serving and consumption for young players. It is necessary to implement information strategies, prevention initiatives, training programs and to support the dialogue between sporting and prevention settings. Although aquabiking has become widespread, the assessment of the intensity for aquatic cycling remains poorly defined. This study investigated the validity of differentiated ratings of perceived exertion (dRPE) recorded from the chest (RPE-chest) and legs (RPE-legs) during aquatic cycling and aimed to determine a simple and accurate estimate of dRPE to regulate aquabiking. Twelve active young subjects performed a pedaling task on an immersed ergocycle using randomly imposed cycling cadences ranging from 50 to 100 rpm in 3-minute steps interspersed by 3-minute active recovery periods. dRPE and cardiorespiratory responses (heart rate [HR]; percentage of heart rate peak value [%HR<inf>peak</inf>]; oxygen uptake [V̇O<inf>2</inf>]<inf>;</inf> and percentage of peak oxygen uptake [%V̇O<inf>2peak</inf>]) were measured during the last minute of each level. The data described three-step relationships between dRPE and rpm. RPE-chest and RPE-legs increased linearly only for cadences between 60 and 90 rpm (r=0.81 and r=0.88, respectively; P<0.001). At these cadences, significant relationships were also observed between dRPE and all the physiological data (highest Pearson product moment for %V̇O<inf>2peak</inf> 0.81 for RPE-chest and 0.88 for RPE-legs, P<0.0001). Last, the classic signal dominance from the legs was observed (RPE-legs>RPE-chest, P<0.0001) but was reduced compared with data obtained during dryland cycling, suggesting a modulating effect of the aquatic medium. Cycling cadence was the better estimator of RPE-legs, which seemed to be the more appropriate dRPE to regulate the intensity of aquabiking in a safe range of pedaling rates.Cycling cadence was the better estimator of RPE-legs, which seemed to be the more appropriate dRPE to regulate the intensity of aquabiking in a safe range of pedaling rates.