r during downhill running in the early post-operation phase, but this effect is lost in the longer term. This suggests that healing and neuromuscular adaptation occur over time and may also indicate a dampening of the effect of LET over time. (337 /350 words) LEVEL OF EVIDENCE Level II. Unicompartmental Knee Replacements (UKR) are being performed in patients with increasing demands and life expectancies withsurgical concerns that cemented fixation will not last. Cementless fixation may offer a solution, but the results in different age groups have not been assessed. The effect of ageat surgery on the outcomes of cementless UKRs was investigated. A prospective cohort of 1000 medial cementless mobile bearing UKR were analysed. Patients were categorised into four agegroups (< 55, 55 to < 65, 65 to < 75 and ≥ 75years). Implant survival was assessed using endpoints reoperation, revision and major revision requiring revision knee replacement components. Functional outcomes were assessed. 10year cumulative revision rate for the < 55, 55 to < 65, 65 to < 75 and ≥ 75 groups were 2.1% (CI 0.6-6.1), 1.8% (CI 0.6-5.3), 3.2% (CI 1.5-6.5) and 4.1% (1.7-9.6) with no differences between groups (p = 0.52). Two of the 22 revisions were considered major. The 10year cumulative reoperation rates were 4.5% (CI 2.0-10.0), 3.0% (CI 1.3-6.5), 3.8% (CI 2.0-7.1) and 4.1% (CI 1.7-9.6) with no differences between groups (p = 0.81). The 10year median Oxford Knee Scores were 42.5, 46.5, 45 and 42.5, respectively. The 10year median Objective American Knee Society Scores were 95 for all age groups. The cementless mobile bearing UKR has low reoperation and revision rates and similar functional outcomes in all age groups. Cementless UKR should be used in all age groups and age should not be considered a contraindication. III.III. To present the short- to midterm clinical outcomes of a series of patients with isolated acute syndesmosis instability treated with arthroscopy and percutaneous suture-button fixation. A review of 17 patients treated through the arthroscopic approach. The mean age of the patients was 27.8years and the mean follow-up was 31.5months. Clinical and functional evaluations were based on the VAS, AOFAS ankle-hindfoot score and time of return to preinjury level of activities. Imaging analysis was performed with stress radiographs, MRI and CT scan with stress. The average VAS was 0.5 and the mean AOFAS score was 95.5. Out of the 17 patients, 15 were able to return to their preinjury level of activities. The mean time of return to activities was 5.06months. Arthroscopic approach and percutaneous suture-button fixation provided satisfactory clinical and functional results for selected patients with ASI at short- to midterm follow-up. Level IV, retrospective case series.Level IV, retrospective case series.A 2D ultrathin MXene nanosheet was prepared under controlled conditions and employed as a sensitive film to construct a QCM (quartz crystal microbalance) humidity sensor by a dip coating method. The MXene nanosheets were obtained by dislodging the element A from the MAX phase by a facile liquid phase etching method. The morphology and composition of the MXene nanosheets were characterized by means of a number of advanced instruments. It was found that the sample is an ultrathin graphene-like nanosheet. The sensing test results showed that the sensor has a 12.8 Hz/% RH sensitivity, 6 s and 2 s (@ 90%) response/recovery time, maximum humidity hysteresis of 1.16% RH, good stability, and selectivity. Finally, the enhanced humidity response mechanism of the MXene nanosheets was explored by density-functional theory (DFT) calculation and experimental verification. The DFT simulation together with comparison of fluoride-free sample revealed that F elements on the surface of the MXene nanosheets play a more important role in improving humidity responses than OH groups. The results present a new strategy to enhance humidity sensing performance of sensing materials by F- doping or decoration. Thus, the sensor has bright potential for humidity sensing.The purpose of the present work was to determine the response in growth performance and spermatozoa characteristics of Windsnyer boars supplemented with progressive levels of α-tocopherol. Twenty Windsnyer boars aged 12 weeks with an average body weight of 19.5 ± 2.67 kg were used. Each boar was housed individually in a 1.54 × 0.8 m pen in environmentally controlled house with the temperature ranging from 22 to 25 °C. Five boars were randomly assigned to each diet containing 0, 40, 70 and 90 IU of α-tocopherol. The growth performance experiment lasted for 12 weeks. Subsequently, boars were humanely slaughtered for analyses of testicular development and spermatozoa characteristics. Polynomial regression was used to analyse data. There was a linear response (P less then 0.05) in average daily gain and feed conversion ratio as α-tocopherol levels increased. Left and right testicular weights showed a linear increase (P less then 0.05) with increasing levels of α-tocopherol. Weights of left and right epididymis exhibited quadratic response (P less then 0.05). Seminiferous tube area responded in a quadratic fashion (P less then 0.05). There was a quadratic relationship (P less then 0.05) between semen volume, straight-line velocity and live spermatozoa. Dead spermatozoa and head abnormalities exhibited linear decrease (P less then 0.05). Selleck PFI-6 In conclusion, inclusion of α-tocopherol improved growth performance and fertility of Windsnyer boars.Two thickness measurement methods using an electron energy loss spectroscopy (EELS) and 10a convergent beam electron diffraction (CBED) were compared in an Fe-18Mn-0.7C alloy. The thin foil specimen was firstly tilted to satisfy 10a two-beam condition. Low loss spectra of EELS and CBED patterns were acquired in scanning transmission electron microscopy (STEM) and TEM-CBED modes under the two-beam condition. The log-ratio method was used for measuring the thin foil thickness. Kossel-Möllenstedt (K-M) fringe of the [Formula see text] diffracted disk of austenite was analyzed to evaluate the thickness. The results prove the good coherency between both methods in the thickness range of 72 ~ 113 nm with a difference of less than 5%.