Glycerol solutions were vaporized and reacted over ceria catalysts with different morphologies to investigate the relationship of product distribution to the surface facets exposed, particularly, the yield of bio-renewable methanol. Ceria was prepared with cubic, rodlike, and polyhedral morphologies via hydrothermal synthesis by altering the concentration of the precipitating agent or synthesis temperature. Glycerol conversion was found to be low over the ceria with a cubic morphology, and this was ascribed to both a low surface area and relatively high acidity. Density functional theory calculations also showed that the (100) surface is likely to be hydroxylated under reaction conditions which could limit the availability of basic sites. Methanol space-time-yields over the polyhedral ceria samples were more than four times that for the cubic material at 400 °C, where 201 g of methanol was produced per hour per kilogram of the catalyst. Under comparable glycerol conversions, we show that the rodlike and polyhedral catalysts produce a major intermediate to methanol, hydroxyacetone (HA), with a selectivity of ca. 45%, but that over the cubic sample, this was found to be 15%. This equates to a 13-fold increase in the space-time-yield of HA over the polyhedral samples compared to the cubes at 320 °C. The implications of this difference are discussed with respect to the reaction mechanism, suggesting that a different mechanism dominates over the cubic catalysts to that for rodlike and polyhedral catalysts. The strong association between exposed surface facets of ceria to high methanol yields is an important consideration for future catalyst design in this area.Artificial metalloenzymes (ArMs) are created by embedding a synthetic metal catalyst into a protein scaffold. ArMs have the potential to merge the catalytic advantages of natural enzymes with the reaction scope of synthetic catalysts. The choice of the protein scaffold is of utmost importance to tune the activity of the ArM. Herein, we show the repurposing of HaloTag, a self-labeling protein widely used in chemical biology, to create an ArM scaffold for metathesis. This monomeric protein scaffold allows for covalent attachment of metathesis cofactors, and the resulting ArMs are capable of catalyzing ring-closing metathesis. Both chemical and genetic engineering were explored to determine the evolvability of the resulting ArM. Additionally, exploration of the substrate scope revealed a reaction with promising turnover numbers (>48) and conversion rates (>96%).Color indices are important quality traits that define the consumer visual acceptance and agroindustrial preferences. Little is known regarding these properties in the commercial almond cultivars grown in Morocco. This work aimed at investigating kernel color indices in five cultivars, namely, "Fournat de Brézenaud," "Tuono," "Ferragnès," "Ferraduel," and "Marcona." Color indices consisted in the following brightness (L ∗), redness index (a ∗), yellowness index (b ∗), chroma (C ∗), hue (H ∗), and metric saturation (S ∗). Measurements were performed over three consecutive growing seasons (2016-2018) across five different sites from northern (Aknoul, Bni Hadifa, and Tahar Souk) and eastern (Rislane and Sidi Bouhria) Morocco. All factors (cultivar, growing season, and site) affected significantly studied color properties; however, genotype was the main variability source. Wide variabilities were found among cultivars. "Marcona" showed the highest L ∗, while "Ferragnès" and "Ferraduel" displayed greater scores of a ∗, b ∗, C ∗, and S ∗. Sidi Bouhria presented the lowest L ∗ but higher a ∗, H ∗, and S ∗. Moreover, Bni Hadifa displayed higher L ∗, b ∗, and C ∗. 2016 (drier growing season) had the highest values of most indices. Principal component analyses (PCA) discriminate all factors through the first three components PC1 (61%, genetic component) and PC2 (30%) and PC3 (7%) which were of environmental nature since they separate sites and growing seasons, respectively. Despite environmental effects, we suggested a possible discrimination among the studied cultivars based on their kernel color indices. Drought conditions during fruit development seemed to improve kernel quality via synthesis of pigments resulting in higher a ∗ and b ∗.A simple, economic, green, and sensitive bioanalytical method for empagliflozin bioassay in rats' plasma was employed successfully owing to the empagliflozin native fluorescence behavior. Enhanced liquid-liquid extraction, using diethyl ether (DEE), was successfully employed for the improved extraction of empagliflozin from rats' plasma based on its high value of logP as 1.8 that boosted the drug migration from plasma to the organic layer. The relative fluorescence intensity for empagliflozin was recorded at emission (299.4 nm) after excitation at 226.5 nm. The method was validated with satisfactory results for linearity (500-5000 ng/mL), trueness, precision, the matrix effect, and extraction recovery. The matrix effect ranged between 15.63% and 23.10% for LQC and HQC samples, respectively. Extraction recovery ranged between 54.61% and 62.54% for LQC and HQC samples, respectively. Ipatasertib datasheet Bias values for the trueness ranged between -10.62 and +14.95, while %RSD values for the precision ranged between 5.39% and 9.33%. The method was successfully applied to rats' plasma samples that included six rats, and the drug concentration was determined in their plasma after 1 hour (estimated Cmax based on literature) following oral administration of empagliflozin with a concentration of 10 mg/Kg, p.o.. The developed cost-effective spectrofluorimetric method in the present work will be of beneficial use in further pharmacokinetic studies that include rats' plasma and biological fluids. Moreover, with the suitable modifications, the described novel extraction of empagliflozin could be adopted to human plasma samples and future clinical studies. Moreover, development of new simple cost-effective methods is necessary to give the researchers a set of "varieties" that they can use according to the laboratory limitations, especially in the developing countries in addition of being a greener method due to the lower consumption of toxic solvents and lower waste production.