All techniques pointed towards a cortical region, where a 7T brain MRI identified a signal alteration consistent with focal cortical dysplasia. A tailored resection of the lesion located in the inferior frontal sulcus was performed, guided by intraoperative electrocorticography (strip and depth electrodes). Postoperative seizure freedom was achieved. The histopathology confirmed the suspicion of focal cortical dysplasia type IIa. With this case report, we highlight the importance of a multimodal approach in the presurgical evaluation of candidates for epilepsy surgery, which, in selected cases, may allow invasive procedures, such as stereo-EEG, to be avoided in the investigation of the epileptogenic zone. Moreover, we underline the pivotal role of EEG source imaging, especially when focal cortical dysplasia is suspected.In last decades, the number of adult patients requesting orthodontic treatments has increased. Orthognathic surgery allows correction of skeletal dysmorphoses in adults. The management of osteoporotic patients treated with bisphosphonates is a major challenge for orthodontists and maxillofacial surgeons. Few studies have been conducted in these patients and four cases of orthognathic surgery have been described to date. A rare case of orthodontic surgical treatment in an osteoporotic patient who has been treated with bisphosphonates is reported. A 38-year-old patient wishing to improve the aesthetics of her face presented in dentofacial orthopedic consultation. Anamnesis revealed a history of bisphosphonate treatment for osteoporosis. The patient presented a hyperdivergent skeletal class III with laterognathia. The occlusal diagnosis was a class III with premolar and canine open bite, interincisal media discordance and dental crowding. The patient was treated by orthodontics and maxillomandibular osteotomy. A postoperative bone Healing delay of four weeks was recorded. This case report discusses the possibility of performing orthodontic treatment associated with orthognathic surgery in patients treated with bisphosphonates in context of osteoporosis. Orthodontics and maxillofacial surgeons must be prepared for the management of patients treated with bisphosphonates. Studies should be considered in order to specify the optimal methods of management.Although adult patients are said to be demanding in terms of discretion of the orthodontic appliance, the factors influencing the choice of the appliance are still poorly understood. The main objective of this study was to determine if there is a correlation, in adults, between the importance of the orthodontic treatment need and the aesthetic preference of the orthodontic appliance (metal braces, ceramic braces in buccal, lingual or aligner). The secondary objectives were to evaluate the impact of the patient's personal factors, his eventual orthodontic past and his perceived orthodontic need. Patients were interviewed by questionnaire before the first consultation. An index, depending of the discretion of the appliance, was used. The need for treatment was calculated via dental health component and aesthetic component of IOTN. LW 6 in vivo Given the size of the sample, only trends can be emitted. The real need for treatment had no influence on the choice of the aesthetic appliance. The most demanding patients would be women, in their thirties, single, employed, executive or practicing a higher profession, with previous orthodontic treatment and having recently consulted an orthodontist, as an adult. These patients felt that their orthodontic treatment need was minimal or significant. Patients estimated the duration of treatment at 17 months. Lingual was considered the most aesthetic appliance far ahead of the aligners. A larger scale study is needed to determine the influence of each factor.Posterior open bite is a malocclusion characterized by the absence of vertical contacts between the occlusal surfaces of the posterior teeth of the opposing arches. It can be uni- or bilateral and involve one tooth or more. Several aetiologies of these posterior open bite have been described, including pathological eruptions, dento-maxillary dysmorphosis and temporo-mandibular dysfunctions. When considering a correction or compensation, there are several therapeutic options (orthodontic and/or surgical and/or prosthetic). Recent developments in adhesive dentistry (bonding biomaterials, ceramics and composites) have made possible the development of more conservative approach for restorative and prosthetic treatments. In order to understand the possible use of these restorations and the help it can provide in our treatment plan, we have selected three original clinical situations. Each one illustrated a posterior open bite aetiology and explained the rehabilitation strategies chosen (process of decision making and realization). Partial bonded restorations (direct composites, overlays, tabletops, veenerlays) can be considered to compensate open bite, in case of impossibility, failure or as a complement of orthodontic treatments. Additive equilibration is not described in the literature for the compensation of posterior open bite, despite the many functional advantages along a simple and conservative technique.In this study, the utility and diagnostic accuracy of alkaline phosphatase on the surface membrane of neutrophils (mNAP) for bacteremia in patients with systemic inflammatory response syndrome (SIRS) was investigated and assessed. A total of 149 patients with SIRS were included. mNAP values were significantly higher in bacteremic SIRS group compared with that in non-bacteremic SIRS group (P less then 0.001). The mNAP levels were significantly higher in SIRS patients with gram-negative bacteremia than those with gram-positive bacteremia. (P less then 0.001). The receiver operating characteristic (ROC) curve analysis revealed the areas under ROC (AUC) of 0.806 for mNAP in differentiating SIRS patients with bacteremia from those without, similar to that for procalcitonin (PCT) (0.797). Combination of PCT and mNAP gave an AUC of 0.841. mNAP shares a similar diagnostic accuracy to PCT in predicting bacteremia in SIRS patients. The combination of mNAP and PCT provides a better prediction of bacteremia in patients with SIRS than either test alone.