To develop a "knowledge-attitude-practice" questionnaire as an evaluating tool of foreigners' cognition on TCM treatment, so as to promote the internationalization of TCM. The questionnaire was based on the "knowledge-attitude-practice" model and adjusted by expert consultation using the Delphi method. After conducting a survey among foreigners, Cronbach's and exploratory factor analysis were used to test the internal consistency reliability and structural validity of the questionnaire, respectively. A total of 10 experts participated in two rounds of expert consultation. The recovery rates of two rounds of expert consultation form were 100.0%. The coefficient authority in two rounds of expert consultation was 0.87 and 0.88, respectively. The concentration of expert opinions in the knowledge, attitude, and practice dimensions was 3.80 to 4.70 points, 3.70 to 4.50 points, and 3.60 to 4.40 points, respectively, in the first round and 4.30 to 4.80 points, 4.10 to 4.60 points, and 4.00 to 4.50 points, revely. Exploratory factor analysis extracted 3 factors with a cumulative contribution of 54.090%. After testing reliability and validity, 1 item was deleted, leaving 29 items. After two rounds of expert consultation based on the Delphi method, the results of expert authority, expert coordination, and expert opinions' concentration were promising, and the expert consultation results were reliable. The "knowledge-attitude-practice" questionnaire of foreigners on TCM treatment in English had good reliability and validity and can evaluate foreigners' cognition on TCM treatment.After two rounds of expert consultation based on the Delphi method, the results of expert authority, expert coordination, and expert opinions' concentration were promising, and the expert consultation results were reliable. The "knowledge-attitude-practice" questionnaire of foreigners on TCM treatment in English had good reliability and validity and can evaluate foreigners' cognition on TCM treatment. To explore whether acupuncture and moxibustion can prevent disease progression of advanced gastric cancer patients completing second-line chemotherapy and, if so, the related mechanism. Progression-free survival (PFS) and overall survival (OS) were main outcome measures. The real-time quantitative PCR was used to detect the expression of genes including T-bet, IFN- , GATA3, and IL-4 in peripheral blood mononuclear cells (PBMCs). IL-4, IL-6, Ca199, CRP, and IFN- in plasma levels were checked. 170 patients were randomly assigned in a 3  2 ratio to receive either acupuncture and moxibustion or sham acupuncture until progression. 135 patients were included in the primary analysis. Both PFS and OS in treatment group were proven to be better than control group. Acupuncture and moxibustion promoted typical Th1 cells drifting, as confirmed by increased T-bet/IFN- and decreased GATA3/IL-4 in mRNA levels from PBMCs, as well as upregulating IFN- and downregulating IL-4 in plasma levels. IL-6, Ca199, and CRP in plasma levels were also reduced by acupuncture and moxibustion. Acupuncture and moxibustion can prolong PFS and OS of advanced gastric cancer patients completing second-line chemotherapy by reversing Th1/Th2 shift and attenuating inflammatory responses.Acupuncture and moxibustion can prolong PFS and OS of advanced gastric cancer patients completing second-line chemotherapy by reversing Th1/Th2 shift and attenuating inflammatory responses. It is generally considered that traditional Chinese medicine (TCM) therapy postpones the progression of some chronic kidney diseases (CKDs). Chinese medicine herbs are widely applied in TCM therapy. We aimed to evaluate clinical efficacy and safety of Chinese herbal formula granules in patients with CKD stage 3 through a prospective randomized controlled study. A total of 343 participants with CKD stage 3 were recruited from 9 hospitals in Jiangsu Province between April 2014 and October 2016. Participants were randomly assigned to a treatment or control group. Patients in the treatment group orally took Chinese herbal formula granules twice a day, while controls received placebo granules. The duration of intervention was 24 weeks. Primary outcomes were 24-hour proteinuria, serum creatinine, and eGFR, which were measured every 4 weeks. There was no statistical difference in 24-hour proteinuria between the two groups (0.97 ± 1.14 g/d vs. 0.97 ± 1.25 g/d). Patients in the treatment group had significantly lower serum creatinine level (130.78 ± 32.55  mol/L versus 149.12 ± 41.27  mol/L) and significantly higher eGFR level (55.74 ± 50.82 ml/min/1.73·m versus 44.46 ± 12.60 ml/min/1.73·m ) than those in the control group (  < 0.05). There was no significant difference between two groups in the incidence of adverse events. The treatment adopting Chinese herbal formula granules for 24 weeks improved kidney function of patients with CKD stage 3.The treatment adopting Chinese herbal formula granules for 24 weeks improved kidney function of patients with CKD stage 3. Herbal formula Gegen-Qinlian Decoction (GQD) has been widely used in China for the treatment of type 2 diabetes mellitus (T2DM), but its efficacy and safety are unclear. The studies were identified from the PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure database, Wanfang database, and VIP database using the keywords "Gegenqinlian" or "Gegen-Qinlian" or "Gegen-Qin-Lian" or "Ge Gen Qin Lian." Relevant studies were selected according to predefined inclusion and exclusion criteria. Study selection, data extraction, and validation were carried out by, at least, two reviewers with disagreements being settled by discussion. After literature search, a total of 26 randomized controlled trials were included with a total of 2553 patients. Sunvozertinib There was evidence that compared with metformin, the combination of GQD and metformin significantly reduced the fasting plasma glucose levels (MD -1.79, 95% CI (-2.31, -1.27), < 0.00001); 2-hour postprandial plasma glucose levels (MD -1.72, 95% CI (-2.