Mechanism analyses showed that NEAT1 serves as a ceRNA to upregulate ABCC4 expression via sponging miR-365a-3p. find more Conclusion In this study, we revealed a NEAT1/miR-365a-3p/ABCC4 triplet in GC progression, which may provide novel targeted therapy markers for GC.[This corrects the article DOI 10.2147/OTT.S177051.].Pulmonary lymphoepithelioma-like carcinoma (PLELC) is a rare and distinct subtype of non-small-cell lung carcinoma associated with Epstein-Barr virus (EBV) infection. We systematically reviewed the recent research that expands our knowledge about PLELC, with main focus on its genetic profile, tumor-infiltrating environment, PD-L1 expression, circulating EBV-DNA, clinical utility of 18F-FDG PET/CT, and treatment strategy. A low frequency of typical driver mutations and widespread existence of copy number variations was detected in PLELC. Persistent EBV infection may trigger intense infiltration of lymphocytes, representing enhanced tumor immunity and possibly resulting in a better prognosis. Circulating EBV-DNA in the plasma of patients with PLELC may predict disease progression and response to therapy. PLELC is 18F-FDG avid, and 18F-FDG PET may help refine palliation strategies and subsequently improve the prognosis. Most of the reported patients present at early and resectable stage, and surgical resection with curative intent is the preferred approach. There is currently no consensus on the regimen of chemotherapy for patients with advanced stages. EGFR-targeted therapies seem to have no therapeutic effect, and the clinical impact of PD-1/PD-L1 therapy is uncertain but worthy of further research.Objective Interrupted time series (ITS) designs are robust quasi-experimental designs commonly used to evaluate the impact of interventions and programs implemented in healthcare settings. This scoping review aims to 1) identify and summarize existing methods used in the analysis of ITS studies conducted in health research, 2) elucidate their strengths and limitations, 3) describe their applications in health research and 4) identify any methodological gaps and challenges. Design Scoping review. Data sources Searches were conducted in MEDLINE, JSTOR, PUBMED, EMBASE, CINAHL, Web of Science and the Cochrane Library from inception until September 2017. Study selection Studies in health research involving ITS methods or reporting on the application of ITS designs. Data extraction Screening of studies was completed independently and in duplicate by two reviewers. One reviewer extracted the data from relevant studies in consultations with a second reviewer. Results of the review were presented with respect to methoss patients and hospital settings.Purpose Interprofessional education (IPE) is defined as a practice of collaboration between two or more students from different health profession programs in which the students study with and about, and learn from, each other. IPE is an educational method that trains students to perform in terms of good communication and teamwork which will be useful for the implementation of interprofessional collaboration (IPC) at health-care facilities. The aim of this study is to identify the perceptions of medicine and health profession students on IPE at Universitas Syiah Kuala, Indonesia. Materials and methods This study was conducted in five health profession programs at Universitas Syiah Kuala, Indonesia. Data were collected using a questionnaire which was then distributed to 286 students sampled with a stratified random sampling method. Analyses were conducted by using a univariate statistical analysis to observe students' perceptions of IPE. Students were considered to have a positive perception if their total score was above the median score. Results More than half of the students (51.4%) in this study had a positive perception toward IPE. However, upon exploration of students' perceptions separately for each study program, only a minority of medical students responded with a positive perception toward IPE (37%). In contrast, the majority of students from dentistry, psychology, nursing, and pharmacy study programs showed a positive perception of IPE, with the pharmacy study program being the program with the highest proportion of students who showed a positive perception (62.5%, 53.5%, 56.4%, and 75%, respectively). Conclusion The majority of medical students show a negative perception toward IPE in contrast to students from other health profession programs at Universitas Syiah Kuala. The pharmacy study program shows the highest proportion of students with a positive perception among all other students.Vascular calcification (VC) is a life-threatening state in chronic kidney disease (CKD). High cardiovascular mortality and morbidity of CKD cases may root from medial VC promoted by hyperphosphatemia. Vascular calcification is an active, highly regulated, and complex biological process that is mediated by genetics, epigenetics, dysregulated form of matrix mineral metabolism, hormones, and the activation of cellular signaling pathways. Moreover, gut microbiome as a source of uremic toxins (eg, phosphate, advanced glycation end products and indoxyl-sulfate) can be regarded as a potential contributor to VC in CKD. Here, an update on different cellular and molecular processes involved in VC in CKD is discussed to elucidate the probable therapeutic pathways in the future.[This corrects the article DOI 10.2147/TCRM.S257421.].[This corrects the article DOI 10.2147/TCRM.S257420.].Purpose The aim of this study was to find the most useful marker of endometriosis-related infertility and evaluate predictive and diagnostic values of systemic inflammatory response markers (preoperative white blood-cell subtypes, neutrophillymphocyte ratio [NLR], plateletlymphocyte ratio [PLR], and monocytelymphocyte ratio [MLR]) and CA125 levels in endometriosis patients. Methods This study comprised 662 women who had undergone laparoscopic surgery and been pathologically confirmed as having endometriosis and 83 patients pathologically confirmed with benign ovarian tumors. Related inflammatory factors in endometriosis complicated by infertility were analyzed via logistic regression analysis. Diagnostic values of the inflammatory response markers were obtained by receiver operating-characteristic analysis. Results We firstly identified that lower NLR level was an independent risk factor of infertility. Serum lymphocytes were significantly higher in endometriosis patients, while serum CA125, NLR, MLR, and PLR were elevated.