QRSA increases the risk of ventricular tachyarrhythmia 4-fold, which merits further study as a risk stratifier. Meniscus has always been the focus of sport medicine with thousands of articles published annually. Few study has tried to analyze these papers with bibliometric methods. The purpose of this study is to statistically analyze the output of meniscus research and determine emerging research trends and hot spots. Papers related to the meniscus published from 2010 to 2019 were downloaded from the Web of Science Core Collection. Information about annual publications and journal distribution was analyzed by Excel 2016. Co-occurrence analysis of the countries/regions, institutions, authors, and keywords were performed with CiteSpace V, which was also used to perform a co-cited analysis of the references and generate corresponding knowledge maps as well as detect burst keywords. A total of 10,066 articles regarding meniscus were published between 2010 and 2019. The number of articles annual about meniscus increased from 786 to 1300. , the United States, University of Pittsburgh, and LaPrade RF were journal, country, institution, and author with the most publications, respectively. Makris EA et al. in 2011 was the most cited articles, with a citation of 198. Osteoarthritis, tear repair, anterior cruciate ligament, and articular cartilage were keywords with occurrence of more than 500. Meniscal extrusion, scaffold, and tissue engineering were terms with most burst strength. Meniscus-related publications showed a gradual rising trend from 2010 to 2019. Osteoarthritis, tear repairs, and the anterior cruciate ligament are the current research hot spots. Extrusion and scaffolds may be the frontiers of meniscus research in the next few years. IV.IV. Substance users are among the most highly stigmatized individuals by both the public and health care providers. selleck chemical However, no multidimensional scale for measuring substance use stigma for substance use disorders (SUDs) currently exists in Turkey. The aim of this study was to determine the validity and reliability of the Turkish version of the Substance Use Stigma Mechanism Scale (SU-SMS). The study was conducted at the AMATEM (Alcohol and Substance Addiction Treatment Center Clinic). The sample group of this methodological study consisted of 156 participants with SUDs who met the inclusion criteria. "Social-demographics Questionnaire," "The Substance Use Stigma Mechanism Scale," and "Internalized Stigma of Mental Illness Scale" were used for data collection. In the validity-reliability analysis of the scale, language and content validity, explanatory and confirmatory factor analysis, criterion-concurrent validity, Cronbach's alpha coefficient, item-total score correlation, split-half reliability analysis, and test-retest reliability methods were used. Using exploratory factor analysis, it was found that the SU-SMS has five factors. Its five-factor structure was confirmed using confirmatory factor analysis. Its Cronbach's alpha coefficient was .828, and factor loading was between .402 and .971. Analyses indicated that each of the factors of the Turkish version of the scale had high internal consistency. The test-retest correlation value was .752, = .000. It was concluded that the Turkish version of the SU-SMS is a reliable and valid instrument for assessing substance use-related stigma in individuals with SUDs.It was concluded that the Turkish version of the SU-SMS is a reliable and valid instrument for assessing substance use-related stigma in individuals with SUDs. The purpose of this study was to evaluate the feasibility and short-term impact of a brief opioid overdose prevention and mitigation training administered to detained youth at risk for witnessing an overdose. Adolescents seen in the medical clinic in a youth detention center were screened to determine risk for witnessing an overdose. Eligible adolescents completed a pretraining assessment that included opioid witnessing experiences and knowledge of and attitudes toward opioid overdose prevention. Participants completed a one-on-one overdose first aid training, received a naloxone (Narcan) kit at release, and completed a posttraining assessment of knowledge and attitudes. At 1 month and 3 months postrelease, participants completed telephone interviews to report satisfaction and application of training concepts. A total of 39 adolescent residents participated in this pilot study. Rates of recruitment and retention, as well as high rates of witnessing opioid use and overdose, indicate that opioid overdose prevention interventions are warranted with this population. There were significant changes in knowledge, confidence, and readiness to intervene in an opioid overdose from pre- to posttraining. At follow-up, the majority of participants still possessed their naloxone, and all reported sharing information from the training with others and having a plan if they witnessed an overdose. One participant reported completion of an overdose reversal. Opioid overdose prevention training with detained youth is feasible and shows promising impacts on knowledge and application, meriting the need for future research.Opioid overdose prevention training with detained youth is feasible and shows promising impacts on knowledge and application, meriting the need for future research. Tuberculosis (TB) remains a major global health burden. There still remains a large gap between the notified and estimated incident cases. Extrapulmonary (EP) TB represents 15% of all TB cases and the diagnosis is more challenging due to the paucity of the organism. Smear microscopy is often insensitive and culture methods are prolonged. With the introduction of Xpert MTB/RIF and more recently Xpert Ultra, this has changed TB diagnostics by providing a rapid accessible platform to diagnose TB and identify rifampicin resistance within 2h. The diagnostic accuracy and the clinical role of Xpert MTB/RIF and Xpert Ultra in the different forms of EPTB. Whilst significant advances have been made in TB diagnostics, there is still a need to optimize the diagnostic yield of Xpert MTB/RIF and Xpert Ultra in EPTB samples. Research is needed to facilitate standardization and optimal preparation of samples as well as understanding the role of Xpert MTB/RIF and Xpert Ultra in different burden settings. Alongside the current GeneXpert platform, the launch of rapid second-line drug resistance polymerase chain reactions and whole genome sequencing may help tackle the global health burden with a more comprehensive diagnostic approach and appropriate treatment.